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Alira Health

Principal, Statistical Programmer

Toronto, ON, Canada

Full-time

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Job details

Job type: Full-time
Experience: At least 5 years of experience in statistical programming
Posting language: English
Posted: Oct 30, 2026

Original job description

🔗Are you being referred to one of our roles by a connection in Alira Health? If so, please apply using the referral link emailed to you.

Join our global team dedicated to innovation and initiative, where physical walls and different time zones don’t limit, but encourage, collaboration. Where all contributions and new ideas are explored with an open mind and work is driven by our shared values: be courageous, be accountable, be honest, be inclusive and elevate others.

Job Description Summary

Job Description

ROLE

The Principal Statistical Programmer will support and lead statistical programming activities conducted on client clinical projects, including complex projects; producing high quality deliverables to agreed timelines and following relevant standard operating procedures. The principal statistical programmer will also support in the effective deployment of project resources and will support the maintenance of an efficient statistical programming department.

KEY RESPONSABILITIES

Lead statistical programming activities on clinical projects including complex projects
Provide support in the identification of changes in project scope and potential risks to contractual delivery
Act as support statistical programmer on clinical projects
Specify, program and validate CDISC SDTM and ADaM datasets
Specify, program and validate the statistical analysis results including analysis datasets, tables, listings and figures
Produce and review CDISC documentation
Create and validate randomization lists
Ensure compliance to SOPs
Report deviations, KPIs, customer complaints and managing CAPAs
Provide supervision on tasks carried out by statistical programmers
Provide guidance and mentoring to programming team members on procedures and technical standards
Prepare and perform internal or external training on statistical programming techniques
Identify, implement and develop new techniques, solutions, tools and products
Identify areas for efficiency or process improvement
Lead internal initiatives to improve department processes
Communicate effectively with internal and external project teams
Report issues to Project Manager/Associate Director in an appropriate timeframe
Support Quality Assurance in internal and external audits
Support the maintenance of an effective statistical programming department
Conduct other statistical programming related activities as required

DESIRED QUALIFICATION & EXPERIENCE

BSc/MSc or equivalent with experience, preferably in Statistics, Computer Science, or Mathematics
At least 5 years of experience in statistical programming
Excellent SAS programming skills
Knowledge of R language is a plus
Very good knowledge of principles and techniques for clinical research

TECHNICAL COMPETENCES & SOFT SKILLS

Good English communication
Good computer skills, with proficiency in use of Microsoft Word, Excel and PowerPoint
Quality focused and results orientated
Confident leader of teams
Ability to effectively prioritize
Trustworthy and strong team player
Willingness to learn
Ability to explain complex Statistical Programming concepts clearly
Analytical thinking and problem solving skills
Innovative thinker

Languages

English

Education

Bachelor of Science (BS): Computer and Information Science, Bachelor of Science (BS): Mathematics, Bachelor of Science (BS): Statistics

Contract Type

Regular

Salary Range

The final offer will be determined within the applicable location-specific range and will depend on the candidate’s confirmed work location, relevant experience, skills, qualifications, internal equity, and role scope.

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More about this job

Responsibilities

The Principal Statistical Programmer leads statistical programming activities for complex clinical projects, ensuring high-quality deliverables and adherence to timelines. They also provide technical guidance, mentor team members, and contribute to process improvements within the department.

Requirements

Candidates must hold a Bachelor's or Master's degree in Statistics, Computer Science, or Mathematics with at least 5 years of relevant experience. Proficiency in SAS programming and knowledge of CDISC standards are essential requirements for this role.

Skills

Statistical Programming
SAS
R
CDISC
SDTM
ADaM
Clinical Research
Data Validation
Project Management
Mentoring
Analytical Thinking
Problem Solving
Quality Assurance
Technical Documentation
Leadership

Visa sponsorship

Not detected in the job text

Keywords

Statistical Programming
Clinical Trials
SAS
R
CDISC
SDTM
ADaM
Data Analysis
Clinical Research
Validation
Randomization
SOP
KPI
CAPA
Quality Assurance
Mentoring
Project Management
Process Improvement
Statistics
Computer Science
Mathematics
Microsoft Office
Leadership
Analytical Thinking
Problem Solving

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