Senior Research Scientist, Method Development (LC-MS)
- Laval, QC, Canada
Full-time
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Job details
- Job type
- Full-time
- Experience
- Typically 5-8+ years of relevant experience in LC-MS/MS bioanalysis, with demonstrated experience independently leading bioanalytical method development projects.
- Posting language
- English
- Posted
Original job description
About The Role
We are seeking a highly motivated and experienced Senior Research Scientist with strong expertise in bioanalytical mass spectrometry to join our Method Development team. The successful candidate will lead the development and optimization of regulatory-ready bioanalytical methods using liquid chromatography-mass spectrometry (LC-MS/MS) for a variety of therapeutic modalities, including small molecules, peptides, biologics, biomarkers, and oligonucleotides.
What You’ll Do Here
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences’ Benefits Package Includes
We are seeking a highly motivated and experienced Senior Research Scientist with strong expertise in bioanalytical mass spectrometry to join our Method Development team. The successful candidate will lead the development and optimization of regulatory-ready bioanalytical methods using liquid chromatography-mass spectrometry (LC-MS/MS) for a variety of therapeutic modalities, including small molecules, peptides, biologics, biomarkers, and oligonucleotides.
What You’ll Do Here
- Develop and optimize robust bioanalytical methods using LC-MS/MS in compliance with regulatory standards.
- Perform and oversee sample preparation, analysis, and data interpretation while meeting project timelines and quality expectations.
- Investigate and resolve complex bioanalytical challenges through systematic troubleshooting, experimental design, and root-cause assessment.
- Participate in client discussions and scientific meetings, communicating method development strategies, analytical results, and technical recommendations.
- Prepare, review, and approve method development reports, SOPs, and other technical documentation as required.
- Collaborate with validation and operational teams to support successful method transfer and implementation.
- Stay current with advancements in LC-MS technologies and best practices to support continuous improvement.
- Adhere to Health and Safety protocols, including personal protective practices and laboratory upkeep.
- Master’s or Ph.D. in Biochemistry, Chemistry, Analytical Chemistry, or a related discipline; a Bachelor’s degree with significant relevant experience may also be considered.
- Typically 5-8+ years of relevant experience in LC-MS/MS bioanalysis, with demonstrated experience independently leading bioanalytical method development projects.
- Experience in sample preparation techniques appropriate to the analyte type (e.g., protein precipitation, solid-phase extraction, immunoaffinity-based approaches, enzymatic digestion).
- Strong scientific writing, communication, and presentation skills, with the ability to effectively communicate complex technical concepts to both scientific and non-scientific stakeholders.
- The requirement to have study protocols read and documented in English as required by industry regulatory agencies
Altasciences offers a wide variety of benefits to help our employees live healthy and fulfilling lives both at and outside of work.
Altasciences’ Benefits Package Includes
- Health/Dental/Vision Insurance Plans
- 401(k)/RRSP with Employer Match
- Paid Vacation and Holidays
- Paid Sick and Bereavement Leave
- Employee Assistance & Telehealth Program
- Training & Development Programs
- Employee Referral Bonus Program
- Annual Performance Reviews
More about this job
Responsibilities
The Senior Research Scientist will lead the development and optimization of regulatory-ready bioanalytical methods using LC-MS/MS for various therapeutic modalities. They will oversee sample preparation, data interpretation, and collaborate with teams to ensure successful method transfer and documentation.
Requirements
Candidates must hold a Master’s or Ph.D. in a relevant scientific discipline with 5-8+ years of experience in LC-MS/MS bioanalysis. Strong expertise in sample preparation techniques and the ability to communicate complex technical concepts to stakeholders are essential.
Skills
- LC-MS/MS
- Bioanalytical method development
- Mass spectrometry
- Sample preparation
- Data interpretation
- Troubleshooting
- Experimental design
- Regulatory compliance
- Scientific writing
- Protein precipitation
- Solid-phase extraction
- Immunoaffinity-based approaches
- Enzymatic digestion
- Technical documentation
- Communication
Benefits
- Health insurance
- Dental insurance
- Vision insurance
- 401(k)
- RRSP
- Employer match
- Paid vacation
- Paid holidays
- Paid sick leave
- Bereavement leave
- Employee assistance program
- Telehealth program
- Training & development programs
- Employee referral bonus program
Visa sponsorship
Not detected in the job text
Categories
- Science & Research
- Healthcare
- Engineering
Keywords
- LC-MS/MS
- Bioanalytical
- Mass spectrometry
- Method development
- Small molecules
- Peptides
- Biologics
- Biomarkers
- Oligonucleotides
- Sample preparation
- Protein precipitation
- Solid-phase extraction
- Immunoaffinity
- Enzymatic digestion
- Regulatory standards
- SOPs
- Analytical chemistry
- Biochemistry
- Troubleshooting
- Root-cause assessment
- Laboratory safety
- Data interpretation
- Method transfer
- Technical documentation