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Astellas Pharma

Clinical Development Physician, Late Stage Oncology

675 Cochrane Drive Suite 650, West Tower, Markham, ON, L3R 0B8, Canada

Full-time

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Job details

Job type: Full-time
Posting language: English
Posted: Oct 26, 2026

Original job description

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Purpose and Scope:

Due to the expanding portfolio, we are looking for Development Physicians/Medical Directors to join our clinical teams in late development Oncology at Astellas.

Responsibilities and Accountabilities:

Core member of the clinical team which is collectively responsible for the design and execution of one or more clinical trials.
Serves as Medical Monitor with responsibility for safety monitoring on clinical studies. Generates safety related documents, such as medical monitoring reports . Collaborates closely with the safety officer in writing and/or reviewing safety narratives, investigator letters, and other safety documentation for site-reported safety events.
With the Development Scientist, responsible for the medical aspects of all study-related documents, including for example the clinical study protocol, informed consent forms, clinical database, safety committee charters and clinical study reports.
Works with Development Scientists and Clinical Operation Leads to ensure efficient and streamlined execution of clinical trials and acquisition and interpretation of high-quality clinical data to inform program-level decision making and overall development strategies.
Supports functional level clinical development related initiatives as needed. Leads and/or participates in scientific and medical training to other team members and external clients, investigators, and other site staff as it pertains to assigned studies.
Reports to the Global Medical Portfolio Lead for Late Oncology.

Qualifications

Required Qualifications:

MD or MD/PhD
Must have 2+ years experience specifically in oncology clinical trial design and execution in a bio-pharmaceutical development organization or a balance of experience at an academic institution and a pharmaceutical company.
Excellent verbal and written communication skills in English.
Experience working in global teams and a global matrixed, remote working environment.
Aware of cultural diversity and how to influence and manage in a multi-cultural organization.
Highest level of scientific integrity and impeccable work ethics

Preferred Qualifications:

Board certified in Oncology or Oncology-related specialty
Experience in solid tumors, preferably Gastro-Intestinal, Thoracic or Genito-Urinary
Experience in late development oncology (Ph3)
Direct experience leading global regulatory marketing authorization submissions and defense of those submissions

Location and Working Environment

This position is based in Ontario, Canada. Remote work from anywhere in Canada except Quebec is available.

At Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.

This position is a global role with strong interaction with various disciplines and international stakeholders

Highly matrixed environment requiring cross-regional coordination.
Frequent interaction with senior leadership and governance bodies.
Collaboration across EU, US, and Japan time zones.

What awaits you at Astellas?

Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors

Values: Innovation, Integrity and Impact sit at the heart of what we do.

Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.

Salary Range

$207,192 - $295,988 annually per year (final compensation will be determined based on a variety of factors, including but not limited to proficiency levels and organizational equity considerations)

*The salary range provided applies to Canada only and does not apply to any other locations outside of Canada.

Benefits:

Medical, Dental and Vision Insurance
Generous Paid Time Off options, including Vacation, Sick time and national holidays
Registered Retirement Savings Plan Program (RRSP)
Company paid life insurance
Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
Long Term Incentive Plan for eligible positions
Wellness programs

Astellas may use artificial intelligence-enabled tools at various stages of the recruitment and selection process.

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More about this job

Responsibilities

Serve as a core clinical team member and medical monitor, contributing to the design and execution of oncology trials and overseeing study safety. Partner with development scientists and clinical operations teams on study documents, data quality and interpretation, program decisions, and medical training.

Requirements

Requires an MD or MD/PhD and at least two years of oncology clinical trial design and execution experience in biopharmaceutical development or a combination of academic and pharmaceutical experience. Candidates must have strong English communication skills, experience in global and multicultural teams, and high scientific integrity; oncology board certification, late-stage trial experience, and regulatory submission leadership are preferred.

Skills

Oncology Clinical Trial Design
Clinical Trial Execution
Medical Monitoring
Safety Monitoring
Clinical Development
Clinical Study Protocol Development
Safety Documentation
Clinical Data Interpretation
Global Team Collaboration
Regulatory Marketing Authorization Submissions
Scientific Communication
Cross-Functional Coordination
Late-Stage Oncology
Solid Tumor Oncology
Risk Management
Cultural Awareness

Benefits

Medical Insurance
Dental Insurance
Vision Insurance
Paid Time Off
Vacation
Sick Time
National Holidays
Company-Paid Life Insurance
Annual Corporate Bonus
Quarterly Sales Incentive
Long-Term Incentive Plan
Wellness Programs

Visa sponsorship

Not detected in the job text

Keywords

Oncology
Clinical Development
Late-Stage Development
Phase 3 Clinical Trials
Clinical Trial Design
Clinical Trial Execution
Medical Monitoring
Safety Monitoring
Safety Narratives
Investigator Letters
Clinical Study Protocols
Informed Consent Forms
Clinical Databases
Safety Committee Charters
Clinical Study Reports
Clinical Operations
Clinical Data
Program-Level Decision Making
Development Strategy
Regulatory Marketing Authorization Submissions
Solid Tumors
Gastrointestinal Oncology
Thoracic Oncology
Genitourinary Oncology
Global Teams
Cross-Regional Coordination
Multicultural Collaboration
Medical Training

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