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AstraZeneca

Clinical Trial Engagement Lead (12-month contract)

BC, Canada
ON, Canada
Virtual - British Columbia, Canada

Full-time

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Job details

Job type: Full-time
Apply by: Oct 9, 2026
Experience: Minimum 4 years of experience in Clinical Operations or other related fields (Sr.
Posting language: English
Posted: Oct 2, 2026

Original job description

Note** This is a 12-month contract

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office and in downtown Toronto are purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.

The Clinical Trial Engagement Lead – Oncology drives a best-in-class site relationship model to position AstraZeneca as the Sponsor of Choice for clinical sites. This role builds and sustains strategic, long-term relationships with key Oncology institutions, including deep engagement with Key External Experts (KEEs) and operational leaders (investigators, site managers, study coordinators, regulatory, pharmacy etc.) to align on trial needs, remove barriers, and elevate the site experience. Acting as the primary interface for clinical trials, the role enhances AZ’s local reputation and optimizes clinical trial environments for timely, high-quality delivery. Key accountabilities include implementing local site relationship strategies (including Partner in Care Network where applicable), monitor and support study start-up on-time enrolment and database flow for the sites they have been assigned and escalate findings from vendor monitoring activities . The role collaborates across clinical, legal, contracts, vendors, and other functions.

Accountabilities:

End-to-end site delivery: Ensure comprehensive site management to achieve enrollment readiness, recruitment goals, and timely locks, including performance management, issue mitigation, and resolution.
Maximize enrollment and experience: Identify and implement opportunities to maximize enrollment timelines while delivering an unparalleled clinical trial and customer experience for investigators, site staff, and patients.
Scientific and regional insight: Apply provided scientific, therapeutic area information, and institutional/regional knowledge to inform feasibility, strategic site allocation, and delivery of high-quality data; understand the provided AZ oncology tumour strategy map and how ongoing/planned AZ studies complement evolving treatment strategies to maximize patient benefit, align with site priorities, and support timely enrolment.
Strategic relationships and networks: Build and expand strategic institutional/site partnerships across academic centers, community practices, and emerging models (hybrid networks, DCT-enabled sites); engage KEEs, investigators, research coordinators, and site leadership to optimize trial delivery across therapeutic areas where applicable.
Data-driven decisions: Leverage site/country/regional metrics and KPIs (quality and performance) to guide decisions, track compliance with partnership agreements, diagnose issues, and drive corrective actions.
Barrier removal and issue escalation: Collaborate with internal teams to remove execution barriers at site and country levels; serve as an escalation point for site performance issues and implement targeted action plans. For outsourced study raise obstacles/issue to global team to drive for resolution.
Operational excellence and standardization: Create and implement strategic partnership frameworks for priority sites; identify, disseminate, and standardize best practices across local operations; contribute to internal cross-functional process improvement initiatives.
Environmental surveillance and strategy: Conduct strategic environmental surveillance within country/market Site to anticipate regulatory and operational changes; provide insights to leadership on site landscape trends, operational risks, and emerging engagement models to shape innovative partnerships.
Cross-functional collaboration: Partner with Feasibility, Clinical Operations, Legal, Contracts, Medical Affairs, CROs, and LOC teams to align priorities, optimize site placement, and deliver the portfolio; act as an effective communication bridge between sites, vendors, and AZ.
Patient-centric impact: Champion patient-centric solutions and representative strategies tailored to oncology populations; enhance collaboration between sites and clinical teams to improve performance and resolve obstacles during start-up and execution.

Required:

Bachelor degree in related discipline, preferably in life science, or equivalent qualification (*).
Minimum 4 years of experience in Clinical Operations or other related fields (Sr. CRA, Site Engagement, Medical Affairs-led or Academic-led studies).
Understanding of international guidelines ICH-GCP as well as relevant local regulations.
Strong client relationship and management abilities.
Good understanding and keen interest in digital solution and technology
Excellent organisational skills and ability to prioritize and handle multiple tasks.
Excellent verbal and written communication skills.
Excellent attention to details
Excellent knowledge of spoken and written English.
Strong negotiation skills and influential leadership skills.
Ability to learn and to adapt to work with IT systems.
Excellent problem solving and conflict resolution skills
Ability to look for and champion more efficient and effective methods/processes of delivering clinical trials to plan focusing on key performance metrics of speed, quality, cost
Manages change with a positive approach to the challenges of change for self, team and the business. Sees change as an opportunity to improve performance and add value to the business
Ability to work across various studies and indications, collaborate with multiple LSTs and GSTs, as needed
Integrity and high ethical standards
Ability to travel nationally as required.

Desired:

Understanding of medical knowledge and ability to learn relevant AZ Therapeutic Areas.
Ability to work across the portfolio from early to late development
Knowledge of the Drug Development Process.
Excellent understanding of the Clinical Study Process including monitoring.
Very good understanding of the Study Drug Handling Process and the Data Management Process..
Good analytical skills.
Good decision making skills.
Basic ability in handling crisis situations.
Ability to influence strategically and persuade tactfully, to obtain desired outcomes while maintaining effective, positive, organizational relationships
Knowledge of the latest technical and regulatory expectations
Familiarity with the latest research and thinking
Experience in Oncology area

The successful candidate must be willing to travel throughout Western Canada, particularly in British Columbia and Alberta

Are you interested in working at AZ, apply today!

AstraZeneca is committed to taking every reasonable precaution to protect employees, our customers and the healthcare systems in the communities in which we serve. In an effort to protect the wellbeing of our employees and customers, full COVID-19 vaccination is an essential requirement of all positions at AstraZeneca. As such, all offers of employment will be conditional upon either (i) proof of full COVID-19 vaccination or (ii) proof of need for accommodation under relevant human rights legislation, and AstraZeneca’s determination that the requested accommodation can be provided without undue hardship. You will be required to submit proof of full vaccination or proof of need for accommodation during our background screening process.

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.

⠀

Annual base salary for this position ranges from 121,562.40 to 159,550.65.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.

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More about this job

Responsibilities

The Clinical Trial Engagement Lead drives site relationship strategies to position the company as a sponsor of choice while ensuring enrollment readiness and high-quality data delivery. The role acts as a primary interface for clinical trials, collaborating across functions to remove execution barriers and optimize the site experience.

Requirements

Candidates must hold a bachelor's degree in a life science discipline and possess at least 4 years of experience in clinical operations or related fields. Strong knowledge of ICH-GCP guidelines, excellent communication skills, and the ability to travel nationally are required.

Skills

Clinical operations
Site engagement
Oncology
Relationship management
Project management
Strategic planning
Data analysis
Communication
Negotiation
Problem solving
Conflict resolution
Regulatory compliance
ICH-GCP
Clinical trial management
Stakeholder management

Benefits

Contract Benefits Program
Paid vacation
Personal days

Visa sponsorship

Not detected in the job text

Keywords

Clinical Trials
Oncology
Site Management
Sponsor of Choice
KEE Engagement
ICH-GCP
Clinical Operations
Patient-centric
Feasibility
Data Management
Regulatory Compliance
Strategic Partnerships
Vendor Monitoring
Enrollment
Study Start-up
Life Science
Stakeholder Engagement
Performance Management
Environmental Surveillance
Cross-functional Collaboration

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