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AstraZeneca

Director, R&D IT Operational Excellence

Mississauga, ON, Canada
Canada - Mississauga, Canada

Job type: Full-time
Apply by: Oct 8, 2026
Experience: 5-7 years+ experience in operational excellence governance, business operations, organizational effectiveness roles, financial management, and performance reporting
Posting language: English
Posted: Oct 1, 2026

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Original job description

Director, R&D IT Operational Excellence

Mississauga, ON

Hybrid Work- on average 3 days/week from office

The Director, R&D IT Operational Excellence is a senior leadership role responsible for driving governance, operational performance, workforce strategy, financial stewardship, organizational effectiveness, and change adoption across R&D IT.

As a member of the Operational Excellence organization, this role partners with Capability, Portfolio, Finance, HR, Strategy, and Quality leaders to ensure disciplined execution of strategic priorities, effective decision-making, transparent performance management, and alignment to enterprise objectives.

The role serves as the operational leader for assigned R&D IT capability portfolios, overseeing governance, planning, workforce and capacity management, performance reporting, financial oversight, and continuous improvement. The Director connects strategy to execution by establishing scalable, data-driven operating models that improve organizational effectiveness and support AstraZeneca's digital, data, and AI ambitions.

In addition, this role leads enterprise-wide change management across R&D IT, communications, employee engagement, and AI enablement initiatives that accelerate technology adoption, strengthen organizational capability, and enhance the employee experience across R&D IT.

What you'll do

Operational Excellence & Governance

Lead operational excellence activities across assigned R&D IT capability portfolios, ensuring alignment to organizational objectives and enterprise governance standards.
Partner with senior leaders within R&D IT to identify and assess operational inefficiencies, prioritize, drive process standardization and optimization, automation, and AI-enabled improvements that increase organizational effectiveness, consistency, scalability, and employee productivity.
Partner with R&D IT Operations Leads to facilitate process standardization across functional areas, fostering a collaborative, one-team approach.
Drive operational discipline through governance reviews, compliance monitoring, risk management, and corrective action planning. Provide regular reporting against targets, broken down by functional area, and partner with stakeholders to course-correct where needed.
Lead operational cadences including but not limited to conducting business reviews, governance forums, operational reviews, and planning activities, including defining agenda and recapping decisions and meeting minutes.
Build strong partnerships across Finance, HR, SP&Q, Portfolio Excellence, Enterprise Functions, and broader R&D organizations.
Influence stakeholders across a complex, matrix environment to achieve organizational objectives and drive sustainable outcomes.

Performance Management & Executive Reporting

Own development and consolidation of business, R&D IT and capability scorecards, frameworks, and executive performance reporting. Provide narrative and speaking-note support for senior stakeholders, including presentation materials for executive-level review and quarterly performance storytelling.
Establish, review and maintain operational health indicators & dashboards, KPIs, OKRs, and executive reporting mechanisms.
Translate complex operational, financial, workforce, portfolio, and AI adoption data into concise, actionable insights for senior leadership.
Establish & leverage existing reporting frameworks that improve organizational visibility, accountability, and decision-making.
Supports annual and multi-year planning activities including Mid-Term Planning (MTP), Long-Term Planning (LTP), business planning cycles, strategic roadmaps, and investment prioritization.

Workforce Strategy, Capacity & Resource Management

Support workforce planning activities across assigned portfolios, ensuring workforce capacity aligns with strategic priorities and delivery objectives.
Oversee organizational headcount governance, including permanent employees and Outside Service Providers (OSPs).
Adhere to standards and onitor workforce utilization, organizational capacity, AI and digital skill demand trends, and future capability requirements to proactively identify workforce risks and opportunities.
Lead workforce readiness initiatives focused on AI literacy, digital capability development, and adoption of emerging technologies across R&D IT
Support long-term sustainability goals, including but not limited to reducing our carbon footprint.

Financial Stewardship & Business Operations

Support capability leaders and business partners in business case development, investment planning, value realization assessments, and funding prioritization decisions.
Lead operational oversight of budget performance against plan, financial governance processes, investment tracking, resource-related expenditures, and recommend corrective actions where necessary.
Ensure compliance with AstraZeneca financial policies, governance standards, and planning requirements.

Essential for the role

Bachelor's degree in Business, Information Technology, Life Sciences, Engineering, or related discipline.
Experience in senior stakeholder management and developing executive-level dashboards, KPIs, scorecards, and operational reporting,
5-7 years+ experience in operational excellence governance, business operations, organizational effectiveness roles, financial management, and performance reporting
Experience measuring business outcomes and organizational value derived from digital, automation, and AI investments.
Experience leading cross-functional continuous improvement and organizational transformation initiatives.
Strong analytical and data-driven decision-making skills.
Excellent written, verbal, facilitation, and executive communication skills.

Desirable for the role

Experience supporting Digital, Data, AI, Technology, R&D, or Product organizations.
Pharmaceutical, biotechnology, healthcare, or regulated industry experience.
Experience with strategic planning cycles, investment governance, and business case development.
Knowledge of Lean, Operational Excellence, Continuous Improvement, Agile, or equivalent methodologies.
Experience with workforce planning, supplier governance, and outsourced service provider management.
Experience leading AI adoption, Generative AI initiatives, Copilot deployments, intelligent automation programs, or workforce AI transformation efforts.
Experience leveraging ServiceNow, Power BI, Jira, AirFocus.
Experience with employee engagement or survey programs.
Familiarity with technology adoption and enablement programs in large, matrix organizations.
A can-do attitude and eagerness to build experience across employee engagement, learning & development, and the broader business of R&D.
Confidence in building relationships across the business and constructively challenging behaviors.
Independence and ability to lead a matrix cross-functional team.

Great People want to Work with us! Find out why:

Are you interested in working at AZ? Apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.

⠀

Annual base salary for this position ranges from 147,292.80 to 193,321.80.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.

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More about this job

Responsibilities

The Director of R&D IT Operational Excellence drives governance, operational performance, and workforce strategy across R&D IT portfolios. This role partners with cross-functional leaders to ensure disciplined execution of strategic priorities, financial oversight, and the adoption of digital and AI-enabled improvements.

Requirements

Candidates must hold a Bachelor's degree in Business, IT, Life Sciences, or Engineering and possess 5-7+ years of experience in operational excellence and financial management. Strong analytical skills, executive communication abilities, and experience in organizational transformation are essential for this leadership role.

Skills

Operational Excellence
Governance
Strategic Planning
Financial Stewardship
Performance Management
Change Management
Workforce Strategy
Data-driven Decision Making
Executive Reporting
Process Standardization
AI Enablement
Stakeholder Management
Business Operations
Organizational Effectiveness
Investment Prioritization

Benefits

Flex Benefits
Retirement Savings Program
4 Weeks Paid Vacation
Personal Days
Variable Pay Bonus
Short Term Incentive
Equity-based Long-term Incentive

Visa sponsorship

Not detected in the job text

Keywords

Operational Excellence
Governance
R&D IT
Strategic Planning
Financial Stewardship
Workforce Strategy
Change Management
AI Enablement
Performance Reporting
KPIs
OKRs
Business Operations
Continuous Improvement
Lean
Agile
ServiceNow
Power BI
Jira
AirFocus
Digital Transformation
Investment Governance
Capacity Management
Executive Communication
Data Analytics
Organizational Effectiveness

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