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AstraZeneca

Senior Statistician II

Mississauga, ON, Canada
Canada - Mississauga, Canada

Full-time

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Job details

Job type: Full-time
Apply by: Oct 13, 2026
Posting language: English
Posted: Oct 6, 2026

Original job description

At AstraZeneca, we pride ourselves on crafting a collaborative culture that champions knowledge-sharing, ambitious thinking and innovation – ultimately providing employees with the opportunity to work across teams, functions and even the globe.

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office and in downtown Toronto are purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevent

The Senior Statistician II has sufficient experience working as a statistician in the pharmaceutical industry to be working independently on activities relating to design, delivery and interpretation, preclinical studies, regulatory submissions and/or commercialisation. This individual is able to perform and communicate results of more technical analyses, and able to guide less experienced staff. They have the scope to develop creative statistical ideas and approaches, and to apply them in their work. Competent individual contributor with excellent cross-functional collaboration.

Typical Accountabilities:

The Senior Statistician II may work directly within a project and/or support statistical methodological advances. The accountabilities for supporting projects directly are:

Provide statistical expertise for complex design and interpretation for preclinical or clinical programmes, high level internal governance committees, regulatory submissions and/or commercialisation.
Analyse internal and external information, perform modelling and simulation to inform design decisions and the development of decision criteria.
Develop a Statistical Analysis plan for complex studies and/or project deliveries.
Act as a coach/guide for less experienced statisticians in the production of analysis, supporting graphics and analysis tables for study reports, Global Medical Affairs studies or publications.
Able to analyse, interpret, summarise and communicate results of complex studies.
Contribute to the regulatory submissions including specification of overview documents and response to regulatory questions.
Identify opportunities for the application of modelling and simulation to improve study design.
Identify opportunities to improve the methodology and provide practical solutions for problems.
Identify and apply statistical methodology to improve the process and delivery activities.
Contribute to the development of best practice to improve quality, efficiency and effectiveness.
Accountable for the quality of their statistical work; provide discipline-specific understanding, insight and constructive challenge and take ownership of development needs, seek coaching or training opportunities

The accountabilities for supporting statistical methodological advances are:

Under guidance of a more experienced statistician, produces pragmatic solutions, often within a tight time scale where the emphasis is to deliver first, then refine and develop solutions thereafter.
Draft statistical analysis plans for complex studies.
Provide consultancy within area of expertise to fellow statisticians working within therapeutically aligned statistics groups, as well as medical scientists and other key roles across the business.
Investigate and apply novel statistical approaches, for relevant statistical issues and/or regulatory guidance and/or value demonstration.
Investigate and improve statistical approaches, establish standards and best practice, develop and implement new methodology interacting with external scientists.
Identify new areas where we can add value, developing collaborative relationships with the external scientific/academic community and maintaining academic links.
Contribute to/or lead the development of a process improvement and/or capability area within the Department.
Develop a strong understanding of the pharma business/AZ ways of working
Communicate research and results internally and externally through participation at conferences and journal publications.

Essential:

MSc/PhD in Statistics, Mathematics (containing a substantial statistical component), or recognised equivalent to stats MSc.
Competent statistical programmer (SAS and R).
Knowledge of key technical and regulatory requirements.
Experience of design, analysis and reporting of preclinical or clinical studies in more than one setting.
Communication skills.
Collaboration and team working skills.
Experience and knowledge of statistical methods and applications in study design, analysis and interpretation

Desirable:

Collaboration required
Ability to apply statistical expertise to problems, problem solving and quality focus

Are you interested in working at AZ, apply today!

AstraZeneca is committed to taking every reasonable precaution to protect employees, our customers and the healthcare systems in the communities in which we serve. In an effort to protect the wellbeing of our employees and customers, full COVID-19 vaccination is an essential requirement of all positions at AstraZeneca. As such, all offers of employment will be conditional upon either (i) proof of full COVID-19 vaccination or (ii) proof of need for accommodation under relevant human rights legislation, and AstraZeneca’s determination that the requested accommodation can be provided without undue hardship. You will be required to submit proof of full vaccination or proof of need for accommodation during our background screening process.

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.

⠀

Annual base salary for this position ranges from 109,148.80 to 143,257.80.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.

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More about this job

Responsibilities

The Senior Statistician II provides statistical expertise for complex study designs, regulatory submissions, and commercialization activities. They also act as a coach for less experienced staff and contribute to the development of statistical methodology and process improvements.

Requirements

Candidates must hold an MSc or PhD in Statistics or Mathematics and possess experience in the pharmaceutical industry. Proficiency in SAS and R, along with a strong understanding of regulatory requirements and study design, is essential.

Skills

Statistical analysis
SAS
R
Clinical study design
Preclinical study design
Regulatory submissions
Modelling
Simulation
Statistical programming
Data interpretation
Cross-functional collaboration
Statistical methodology
Project management
Communication skills
Problem solving

Benefits

4 weeks paid vacation
Annual Personal Days
Variable Pay Bonus
Short Term Incentive
Equity-based long-term incentive program

Visa sponsorship

Not detected in the job text

Keywords

Statistician
Pharmaceutical
Clinical trials
Preclinical studies
Regulatory submissions
SAS
R
Statistical analysis plan
Modelling
Simulation
Data interpretation
Methodology
Governance
Commercialisation
Medical affairs
Process improvement
Statistical programming
Study design
Reporting
Collaboration

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