Find work in Canada.

324,429 jobs across our Canadian network. How we count

Jobs in Canada

25+ jobs

Email me new jobs Save this search

Added 10 mins ago
IRATA Level 3 Technician - LNG Kitimat Turnaround
Tacten Industrial Inc
Kitimat, BC
Temporary
Demonstrated ability to lead, instruct, and supervise Level 1 and Level 2 technicians
Added 10 mins ago
Senior Data Scientist
City of Edmonton
AB
Project Leadership: Lead and manage complex data science projects, aligning them with corporate objectives and incorporating project planning, scheduling, resourcing, risk assessment, and…
Added 10 mins ago
Co-op Winter 2027 – Project Engineer - 8 to 12 months
General Dynamics Missions System International
Ottawa, ON
Internship
…Manager (DPM) and the Program Manager (PM) in the execution of development, integration, test, and production, and export of Tactical Communication Systems for the Romanian Ministry of…
Added 10 mins ago
Co-op Winter 2027 – Systems Test Engineering - 4-8 Months
General Dynamics Missions System International
Ottawa, ON
Internship
Perform systems and software test activities, and execute verification tests as directed by the Test Lead to ensure design requirements are met;
Added 10 mins ago
Account Manager, Commercial
Gorgias
Remote, Canada
$80,000 to $89,000 CAD / year
Full-time · Remote
…resources to grow in your role and prioritize your personal development and…
Added 10 mins ago
Process Development Engineer
Entegris
Toronto, ON · Canada - Toronto
Full-time
Entegris is currently seeking a Process Development Engineer to join our Scale-up and Manufacturing Readiness team. This position will be based in our Toronto facility.
Added 10 mins ago
Staff Information Security Engineer - Threat Detection & Response
Visier Solutions Inc
Vancouver, BC
…organizations across the globe. Our mission is to help businesses lead with insight at scale as they continuously…
Added 24 mins ago
Project Manager
Apertera (formerly Alexa Translations)
Montreal, QC
Full-time
…him/her. He/She also plays an integral part in the improvement and development of your processes and we expect a Senior project manager to always have an innovative point of view as to how…
Added 24 mins ago
QPIC Supervisor
Kohl & Frisch Limited
Concord, ON
Full-time
Lead continuous improvement in the security of controlled substances
Added 24 mins ago
Business Analyst, Economic Development Research
City of Mississauga
Mississauga, ON
Full-time
The City of Mississauga is seeking a highly motivated analyst to help guide economic development strategy, business growth initiatives, and investment attraction efforts in one of Canada's…
Added 25 mins ago
Manager Accounting Standards and Policies (Contract)
Sobeys Capital Incorporated or a Franchise/Affiliate / ou une franchise/société affiliée
Mississauga, ON · New Glasgow, NS
…providing accounting advisory support to various areas of finance, lead and contribute to ad hoc projects, overseeing the preparation of audit committee material and ensuring compliance…
Added 25 mins ago
Technology Lead - IOS Developer
Infosys
ON
…technical proficiency across different stages of the Software Development Life Cycle including Requirements Elicitation, Application Architecture definition and Design; play an important…
Added 25 mins ago
Technology Lead - Android Developer
Infosys
ON
…leverage your deep technical expertise across the entire Software Development Life Cycle (SDLC), interfacing with key stakeholders throughout the process. This includes requirements…
Added 25 mins ago
Back of House - Chef Designate
Northland Properties
Hamilton, ON
We are looking for enthusiastic and experienced Chef Designate to lead our culinary teams towards continued success in this ever-evolving industry. As the Chef Designate, you will have the…
Added 25 mins ago
Software Engineer
Roadpost
Toronto, ON
Full-time
Mentor & Lead Technically. Support junior engineers, lead service-level design discussions, contribute to broader engineering initiatives, and build toward ownership or larger initiatives.
Added 40 mins ago
Technical Support and Engagement Specialist, Provincial Programs
OceanMD
Toronto, ON
Full-time
…program pods, partnering closely with our Technical Support Team Lead and provincial support teams to build effective ways of working and strengthen how support is delivered. You will bring…
Added 40 mins ago
Data Architect
Rules Cube
Toronto, ON
Full-time
10+ years of experience in data engineering, data architecture, or related roles, including at least 3 to 4 years in an architect or technical lead role.
Added 55 mins ago
Lifecycle & Marketing Automation Specialist
Newfoundland Capital Corporation Limited
Montreal, QC
Full-time
As Lifecycle Marketing Specialist, you’ll lead the strategy and execution of customer journeys that turn data, technology, and customer insights into measurable business growth. You’ll…
Added 55 mins ago
Manager, CRM and Campaign Systems
Cystic Fibrosis Canada / Fibrose kystique Canada
Toronto, ON · Greater Toronto Area, Canada
$82,240 to $97,660 CAD / year
Full-time
Provides authentic leadership, support and direction in the development, alignment, and accomplishment of objectives through on-going performance feedback, recognition, and coaching.
Added 55 mins ago
Mitigation Operations Manager – Restoration Services
Stoakley-Stewart Consultants Ltd.
Toronto, ON · Greater Toronto Area, Canada
Full-time
Are you ready to step up from managing the work to helping lead the operation?
Added 55 mins ago
Senior Interior Designer
DIALOG
Toronto, ON
Full-time
Lead site visits and field reviews and undertake site deficiency review and installation inspections
Added 55 mins ago
Territory Account Manager
Kohl & Frisch Limited
Concord, ON
Full-time
Reporting to the Senior Director, National Independent Sales, the Business Development Representative (Territory Account Manager) will promote Kohl & Frisch Limited programs to independent…
Added 55 mins ago
Broadcast Solutions Specialist
EvertzAV
Burlington, ON
Full-time
Refine system designs and provide accompanying documentation/requirements captures to help drive development of final specifications and contract terms
Added 55 mins ago
Team Lead, Office Services
Dentons
Vancouver, BC
The Vancouver office is seeking an experienced and service-oriented Office Services Team Lead to join its busy and fast-paced Office Services team. This is a hands-on working lead role that…
Added 55 mins ago
Associate Director, Product Owner (Toronto)
Fitch Group
Toronto, ON
…teams and external clients rely on. In this role, you will lead the discovery and delivery of AI-powered capabilities and workflow automation solutions, partnering across business units to…

AstraZeneca

Site Quality Director

Hamilton, ON, Canada
Canada – Hamilton – Longwood Road South, Canada

Job type: Full-time
Apply by: Oct 16, 2026
Education: Bachelor’s degree
Posting language: English
Posted: Sep 28, 2026

Apply About employer

Applications open in a new tab.

Original job description

Fusion Pharmaceuticals, part of the AstraZeneca Group, is redefining precision oncology with next‑generation radioconjugates that deliver powerful alpha‑emitting payloads directly to tumors. Our pipeline spans multiple first‑in‑class programs - backed by a GMP‑compliant, state‑of‑the‑art radiopharmaceutical facility in Hamilton, we’re turning cutting‑edge science into real‑world impact for patients. Join us at the forefront of radiopharma innovation and be part of turning breakthrough science into meaningful outcomes for patients - come build what’s next with us!

Note: This role is 5 days per week onsite.

Position Summary:

Provide strong site leadership and oversight to ensure responsibilities regarding QA, QC and site compliance activities. The position is accountable for assuring the supply of radio conjugate quality products to markets and ensuring cGMP compliance at the site. Responsible for leading, directing, identifying and setting quality goals, objectives, and perfect execution in alignment with Global Quality Goals. Maintain cGMP compliance at site, including harmonization of procedures in alignment with Global Policies & Standards. Ensuring the materials and products are tested and released in a timely manner by adhering to approved procedures and specifications. Acts as a champion for building a “Culture of Quality” across the organization. Accountable to assure site is always ready for all regulatory inspections.

This role will report directly to the Head of Quality, Radiopharmaceutical.

Responsibilities:

Ensure all finished products intended for use in the market are safe and effective as per cGMP requirements, regulatory commitments, AZ policies & procedures and site SOPs.
Set site quality goals, objectives and strategic direction in alignment with Global Radio Conjugate Quality goals.
Track, trend, maintain and report all Quality and business metrics to monitor and action all QA & QC compliance activities.
Prevent Quality or regulatory non-compliance issues which could lead to product stock-out or withdrawal, product approval delays or which would negatively impact the quality, financial performance and reputation of the company. Non-compliance issues are to be addressed via corrective and preventive actions (CAPA).
Ensure rationalization and management of Quality processes, operations and systems. Perform gap analysis to plan actions for continuous improvements.
Resource planning and monitoring for head count projections, manage site budget, capital budget and manage organizational development.
Responsible for site lean design and execution of continuous Quality & Compliance improvement initiatives, standardizations and efficiency gains to enhance compliance, drive efficiencies and reduce cost of poor quality.
Coach and develop direct and indirect reports, as appropriate, through ongoing, example-based performance feedback, annual performance reviews and the provision of training and development opportunities.
Performs all work in support of our Corporate Values and Behaviors and in accordance with established regulatory and compliance and safety requirements.
Ensure the raw material, packaging material and finished products are tested and released in accordance to approved specification and test methods in a timely manner as per the site commits and support business needs.
Ensure the health authority and Annex 1 requirements at the site are met for sterile products.
Support the development of site strategy to respond to audit observations, inspection findings and implement corrective actions.
Create and maintain 24/7 inspection readiness at the Hamilton site.
Be a solution-oriented leader and role model AZ behaviors.
This is a supervisory position with direct reports; therefore, this position will establish goals and objectives, prepare performance appraisals, monitor/review work product and coach/mentor direct reports.
Other duties as required/assigned.

Minimal Qualifications:

Bachelor’s degree in chemistry, pharmacy or relevant engineering or life science field is required. Candidates with advanced degrees are highly preferred.
This position requires a minimum of fifteen (15) years of experience (10 years + 5 years in leadership capacity) in pharmaceutical quality management, and minimum five (five) years of experience in leadership role.
Significant experience in radio conjugates is preferred with experience in the review and auditing of executed batch records, material release records, and qualification protocols.
A strong knowledge of GMP’s in both domestic and international regulatory environments is required.
Excellent and detailed knowledge of Quality/Compliance processes and programs for development and commercial products including regulatory requirements on a global level; working knowledge of safety and environment regulations and guidelines are also required.
Strong comprehensive knowledge of USFDA 21 CFR regulations Part 11: EC/ER requirements, GMP requirements of various regulatory bodies – USFDA/ MHRA/ EU GMP/ PMDA.
Strong comprehensive knowledge of ICH Guidelines, FDA and Health Canada Regulations.
A proven ability to lead, manage and motivate people with a variety of skill sets is required.
Strong organizational, interpersonal and communication skills are required.
Ability to work effectively in an international matrixed organization is strongly preferred.
Must be on-site (Hamilton, ON) for Quality support of ongoing activities. Role requires off-shift, evening and weekend support.

Knowledge of quality operations and compliance of clinical and commercial aseptic manufacturing.

Must possess excellent written, organizational and communication skills.

At AstraZeneca, we foster a collaborative, innovative culture with opportunities to work across teams, functions, and geographies. You’ll join a collaborative, innovative community with opportunities to work across teams, functions, and geographies - where your ideas move fast and your impact is visible. We’re committed to sustainability and equity, taking bold action on climate, access to healthcare, and disease prevention.

Are you interested in working at AZ, apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.

Apply now and take the first step towards a fulfilling career at Fusion, an AstraZeneca company.

⠀

Annual base salary for this position ranges from 146,404.00 to 192,155.25.

AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues. Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role. The range provided in this posting represents an offer pay range used in a majority of situations. The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs. In some cases, offers outside the range may also be considered to address unique circumstances.

In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role). Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days. Fixed Term Contract/Temporary positions (excluding students) are offered a Contract Benefits Program.

We are using AI as part of the recruitment process.

This advertisement relates to a current vacancy.

Apply About employer

More about this job

Responsibilities

Lead site quality operations and ensure QA, QC, product release, and cGMP compliance for radioconjugate products, including readiness for regulatory inspections. Set site quality strategy and goals, manage quality metrics, resources, budgets, and improvement initiatives, and coach direct reports.

Requirements

A bachelor's degree in chemistry, pharmacy, engineering, or a relevant life science field is required; an advanced degree is preferred. Candidates need at least 15 years of pharmaceutical quality management experience, including at least five years in leadership, along with strong global GMP and regulatory knowledge; radioconjugate experience is preferred.

Skills

Pharmaceutical Quality Management
Quality Assurance
Quality Control
cGMP Compliance
Regulatory Compliance
Radiopharmaceuticals
Aseptic Manufacturing
Quality Systems
CAPA Management
Inspection Readiness
Batch Record Review
Material Release
Audit Management
Continuous Improvement
People Leadership
Strategic Planning

Benefits

Variable Pay Bonus
Equity-Based Long-Term Incentive Program
Flexible Benefits Program
Retirement Savings Program
Four Weeks' Paid Vacation
Annual Personal Days

Visa sponsorship

Not detected in the job text

Keywords

Radioconjugates
Radiopharmaceuticals
Good Manufacturing Practice
Quality Assurance
Quality Control
Site Quality Management
Product Release
Regulatory Compliance
FDA 21 CFR Part 11
Electronic Records
Electronic Signatures
EU GMP
MHRA
PMDA
Health Canada Regulations
ICH Guidelines
Annex 1
Aseptic Manufacturing
Clinical Manufacturing
Commercial Manufacturing
Corrective and Preventive Actions
CAPA
Batch Records
Material Release Records
Qualification Protocols
Regulatory Inspections
Audit Findings
Continuous Improvement
Quality Metrics
Lean Operations

Report this job