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DNAstack

Senior Program Manager

Toronto, ON, Canada

Pay: The salary range for this role is $100,000 to $140,000.
Job type: Full-time
Experience: 5-10 years of hands-on project management experience, within a B2B or SaaS environment
Posting language: English
Posted: Sep 25, 2026

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Original job description

About DNAstack

At DNAstack, our mission is to power precision medicine by building software that breaks down barriers to responsible biomedical data sharing, discovery and analysis. We build cutting-edge software and industry standards to help researchers and clinicians analyze sequencing data and make faster, more accurate diagnoses. Our platform supports national and international networks tackling rare disease, cancer, infectious disease, and more. We're nimble, cross-functional team of scientists, engineers, designers, and product thinkers working at the intersection of genomics, software, and cloud technologies. Our mission is ambitious, and so is our team.

What You’ll Do

We're looking for an experienced Senior Program Manager to join our team for full-time, 14-month contract.

You will own the planning and execution of client projects that drive advancements in areas such as Parkinson’s Disease, ALS, and Autism. Reporting to the Director of Market Development, you’ll be responsible for ensuring timely delivery of contracted deliverables, maintaining strong client relationships, driving contract renewal and extension, and keeping projects aligned with strategic objectives.

You’ll coordinate with internal teams across product, engineering, and design to prioritize tasks, manage dependencies, and ensure smooth execution. You’ll also engage with executive leadership - both internally and within client organizations - to facilitate discussions, understand needs and pain points, and support decision-making.

In addition to overseeing timelines and deliverables, you’ll manage budgets, track progress, and handle reporting, ensuring transparency and accountability. You'll also anticipate risks, develop mitigation strategies, and embed customer success and project management best practices into project workflows.

Your work will directly contribute to advancing cutting-edge research while ensuring efficient and effective collaboration between stakeholders.

Who You Are

You’re a highly organized, detail-oriented person who thrives on keeping projects moving, ensuring teams are aligned and enjoys working with people. You’re a clear and confident communicator - whether it’s crafting a concise report, leading a meeting, or engaging with executives. You can navigate conversations with internal and external leadership teams, ensuring alignment, clarity, and timely follow-through on key initiatives.

You’re process-driven but also happy to roll up your sleeves and handle the tasks that keeps everything on track - agendas, decks, budgets, reports, and deliverables. You take pride in making complex projects feel seamless, balancing both strategic business priorities and day-to-day coordination.

You naturally embed project management and customer success practices into your workflow, collaborating closely with internal teams to ensure delivery meets client needs and drives real impact. You thrive in a fast-paced, agile environment and are excited to contribute to meaningful work in genomics and health research.

Key Responsibilities

Own and drive external client programs, ensuring the successful execution of contracted deliverables, proactively addressing client inquiries, and maintaining high-level stakeholder engagement.
Lead cross-functional collaboration with internal product, engineering, and design teams to drive execution, negotiate priorities, and remove roadblocks.
Identify potential project execution risks and work with internal teams to enact mitigation strategies
Organize and facilitate weekly external and internal meetings, including preparing agendas and presentations, taking minutes, and sending succinct and actionable summary communications
Manage project budgets, external reports, and invoicing, ensuring financial accountability and transparency.
Identify and lead strategic opportunities to expand services to existing and new clients
Serve as a strategic partner to executive leadership teams, providing insights, rationale, and recommendations for decision-making.
Work with leadership to support, develop and model best project management practices
Embed and support customer success practices within all aspects of project management
Drive additional strategic initiatives as needed, based on business needs and opportunities for impact.

Skills

Strong working knowledge of PMBOK process groups and their practical application
Commercial judgement in contract negotiation and scope management
Ability to manage multiple large, complex, multi-stakeholder projects simultaneously
Exemplary written and verbal communication; able to convey complex ideas and strategies to diverse audiences
Excellent collaboration and relationship building
Extremely organized with strong attention to detail
Self-driven and able to work independently, while also maintaining transparency within teams
Proactive leader and problem solver - showcases creativity in addressing challenges, offering solutions to complex problems
Quick learner and curious team player, someone who is unafraid to ask questions
Ability to lead tasks with limited precedents and prior references available
Adaptable and flexible, is able to adjust priorities based on company needs while maintaining external commitments
Possess a strategic mindset with the ability to align project initiatives with broader organizational goals and objectives.

Minimum Qualifications

5-10 years of hands-on project management experience, within a B2B or SaaS environment
Prior experience in a customer-facing role, managing external stakeholders on high-value contracts (e.g. valued at >$1M CAD)
Demonstrated experience delivering complex programs with formal reporting obligations
Experience drafting and managing commercial contracts

Preferred Requirements

Prior experience working with product and/or engineering teams
Previous employment within a small, agile team e.g. startup or small business
Knowledge expertise in technology, data sharing, genomics, or bioinformatics an asset
Experience in customer success, product marketing, or community management
Proficiency with project management and collaboration tooling
Experience in genomics, life sciences, or a regulated technical domain considered an asset
PMP certification is highly preferred

Where You’ll Work

This role offers the flexibility of a hybrid work environment, allowing you to work both remotely and from our Toronto office. This arrangement supports your needs and promotes a healthy work–life balance.

Eligibility

To be considered for this position, you must be eligible to work in Canada.

Benefits

Remote friendly, with flexible hours and the opportunity to work on-site at our Toronto office
Comprehensive health benefits: medical, dental and vision coverage for you and your dependents
Three weeks vacation
Unlimited sick days
Maternity and parental leave top-up programs
One-time remote office set-up stipend
Career development and learning support
Opportunity to contribute to open science and global data-sharing efforts

The salary range for this role is $100,000 to $140,000. At DNAstack, we are dedicated to providing pay transparency to all candidates. Compensation at DNAstack is determined through various factors including but not limited to: comparable salary market data within Canada, technical skill assessment, a holistic view of previous work history, and internal pay equity with other DNAstack team members.

DNAstack is committed to fair and equitable compensation practices. In accordance with the appropriate legislation in each jurisdiction in which we operate, we ensure that our team members are compensated within equal pay ranges for work of equal value, regardless of gender.

We regularly review our compensation practices to identify and address any pay equity gaps. Our approach considers skill, effort, responsibility, and working conditions to ensure that compensation decisions are objective, transparent, and free from bias.

Pay equity is an ongoing process, and we are committed to maintaining compliance with legislative requirements while fostering a workplace that values fairness, respect, and inclusion.

At DNAstack, we are committed to building and fostering an inclusive, accessible environment for everyone. If you have any questions, concerns, or requests regarding accessibility needs at any stage of the interview process, please contact humanresources@dnastack.com and we will work with you to meet your needs.

As a small but mighty team, we use AI-powered tools to help us stay organized and efficient during our hiring processes. These tools help in areas such as sorting applications and highlighting matches to the role. These tools help us move faster, but they definitely don't make decisions for us - every application is reviewed by a real human on our team.

Your privacy matters to us. Any information you share is handled according to Ontario privacy laws as well as our internal privacy practices. If you have any questions about how we use AI in our hiring process, please reach out to humanresources@dnastack.com

Note: this posting is for an existing vacancy that we are seeking to fill.

For compliance reasons, all offers of employment at DNAstack are conditional upon a successful background check that may consist of prior employment verification, reference checks, education confirmation, criminal background, or other information, as permitted by law.

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More about this job

Responsibilities

The Senior Program Manager will own the planning and execution of client projects, ensuring timely delivery of contracted deliverables and alignment with strategic objectives. They will lead cross-functional teams and serve as a strategic partner to executive leadership to facilitate decision-making and drive project success.

Requirements

Candidates must have 5-10 years of hands-on project management experience within a B2B or SaaS environment, including managing high-value contracts. Strong communication skills and the ability to manage complex, multi-stakeholder projects are essential for this role.

Skills

Project management
Stakeholder management
Contract negotiation
Budget management
Cross-functional leadership
Risk mitigation
Customer success
Communication
Strategic planning
Agile methodology
PMBOK
Data sharing
Genomics
Bioinformatics
SaaS
Problem solving

Benefits

Medical coverage
Dental coverage
Vision coverage
Three weeks vacation
Unlimited sick days
Maternity and parental leave top-up
Remote office set-up stipend
Career development and learning support

Visa sponsorship

Not detected in the job text

Keywords

Senior Program Manager
Genomics
Precision medicine
Biomedical data
SaaS
B2B
PMBOK
Agile
Stakeholder engagement
Contract management
Budgeting
Risk management
Customer success
Bioinformatics
Life sciences
Project management
Cross-functional collaboration
Strategic planning
Data sharing
Clinical research

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