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Added 7 mins ago
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Senior Manager, Quality Assurance Services
ATB
Calgary, AB · Edmonton, AB
- Full-time
Ready for tomorrow: We want to enable your success through interesting and challenging work, performance enablement, and learning and development.
Added 7 mins ago
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Senior Mechanical Engineer
Worley
Vancouver, BC
- Full-time
Worley is seeking a Senior Material Handling Engineer / Project Manager to provide senior-level mechanical engineering, materials handling, and project management expertise within the…
Added 7 mins ago
RU
Advisory Manager - Cyber Strategy
RSM US LLP
Toronto, ON
- Full-time
RSM is seeking a Cyber Strategy Advisory Manager to lead large-scale cybersecurity assessments, program transformations, and technology-enabled implementations for complex clients. This…
Added 7 mins ago
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Personal Banking Associate
TD
Estevan, SK
- Full-time
…banking experience. TD is deeply committed to being a leader in client experience, that is why we believe that all colleagues, no matter where they work, are client facing. Together, we are…
Added 7 mins ago
HR
Specialist, Designated Beauty Advisor (DBA) - Chantecaille
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- Full-time
Build a loyal personal client base by constantly acquiring new customers, developing existing clients, and retaining loyal clients
Added 22 mins ago
TG
Analyst
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A Platform for Long-Term Growth: As you develop expertise and judgment, you’ll take on more responsibility, manage client relationships, and contribute to thought leadership. The skills you…
Added 22 mins ago
BG
Technicien·ne d’atelier - Manutention | Heavy Equipment Technician - Material Handling
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- Full-time
Brandt est une entreprise privée et familiale, guidée par le client. Notre solidité repose sur la diversification de nos activités et notre succès sur la spécialisation de nos expertises.…
Added 37 mins ago
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- Full-time
…interpersonal areas to accelerate your path to building a successful client portfolio serving our high-net-worth clients. The program includes enhanced coaching and training and offers…
Added 38 mins ago
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Evergreen Client/Banking Advisor
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- Full-time
Client Advisor Intern – Job ID Code 2251 | Client Advisor – Job ID Code 2252
Added 52 mins ago
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Account Manager
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Burnaby, BC
- Full-time
1-2 years of experience in an account management, client services or customer success role (B2B preferred) and/or post-secondary education in Business, Sales or Marketing
Added 52 mins ago
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Automotive Sales & Finance Consultant
Pfaff Automotive Partners Inc.
Mississauga, ON
- Full-time
If you’re competitive, relationship-driven, and motivated to build your success in the luxury automotive industry, we want to hear from you.
Added 1 hour ago
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Service Delivery Manager
Avanade
Toronto, ON
- Full-time
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Cleaner
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- Part-time
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Added 1 hour ago
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Consultant(e) en intégration (Bilingue) - Integration Consultant (Bilingual)
ADP
Toronto, ON · Etobicoke, ON
- $75,200 to $125,200 CAD / year
- Other
Soutenir les initiatives d’amélioration continue visant les processus d’intégration, les outils et l’expérience client.
Added 1 hour ago
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Consultant(e) en intégration (Bilingue) - Integration Consultant (Bilingual)
ADP
Montreal, QC
- $75,200 to $125,200 CAD / year
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Added 1 hour ago
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Automation Controls Associate Manager
Accenture
Calgary, AB · Vancouver, BC · Mississauga, ON · Ottawa, ON · Toronto, ON
- Full-time
· Maintain and improve client relationships with all engineering disciplines and identify and develop new business opportunities.
Added 1 hour ago
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Credit Analyst I
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Vancouver, BC
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TD Wealth is focused on the delivery of legendary client experiences to Mass Affluent and High-Net Worth clients through an integrated team of professionals across Private Investment…
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Senior Manager, Operational Risk / IT Risk and Compliance
Royal Bank of Canada
Toronto, ON
- Full-time
Senior Manager Operational Risk / IT Risk and Compliance is responsible for supporting the management of Operational Risk and Technology / Cyber Risk supporting the broader Payments…
Added 1 hour ago
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Manager, Premium Services (Rogers Place)
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Edmonton, AB
- Full-time
…food and beverage experiences for our partners and guests. Our success is driven by strong leadership, operational excellence, and a collaborative, people-first…
Added 1 hour ago
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Facility Manager III
BGIS
Toronto, ON
- Full-time
…drive innovation for our clients’ businesses. Globally, we manager over 320 million square feet of client portfolios across 30,000+ locations in North America, Europe, Middle East,…
Added 1 hour ago
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Senior Analyst, Marketing Science
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Toronto, ON
- Full-time
…Offering. We Work To Connect The Media We Plan And Execute With Our Client’s Business Outcomes. Establishing That Relationship Requires Data-focused Capabilities Across 3…
Added 1 hour ago
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Compliance Officer
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…filings and other compliance tasks to help deliver a positive client experience and to improve operational…
Added 1 hour ago
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Regional Operations Manager, Cleaning Services
BGIS
Calgary, AB
- Part-time
Job Summary: Under the general supervision of the Regional Director of Operations the Regional Manager performs a variety of management tasks with emphasis on customer satisfaction and…
Added 1 hour ago
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Finance Manager
BGIS
Markham, ON
- Full-time
Finance Manager is accountable for financial reporting, financial planning and analysis, process development and internal control adherence for a large CBG. The candidate should have a…
Added 1 hour ago
Branch Manager
Talent Acquisition Team at Westland Insurance. Text reply only.
Winnipeg, MB
As a Branch Manager, you're a collaborative sales leader with a genuine passion for the client experience and your team members. You're responsible for all our daily office operations.…

ICON Strategic Solutions

Sr Start-up Manager

Burlington, ON, Canada

Full-time

Apply About employer

Applications open in a new tab.

Job details

Job type: Full-time
Apply by: Nov 26, 2026
Experience: Minimum of 5 years of experience in a Clinical Research environment, focusing on Start-Up.
Posting language: English
Posted: Oct 27, 2026

Original job description

Start-Up Manager

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

What You Will Be Doing

The Study Start-up/Site Activation Lead is responsible at country level for managing and conducting start-up activities in compliance with the client procedures, documents, local and international guidelines such as ICH – GCP and relevant regulations.
The Study Start-up/Site Activation Lead will prepare, review, track and manage site regulatory documentation at country and site level, and will maintain, review and report on site performance metrics.
The Study Start-up/Site Activation Lead works in close collaboration with the CRAs and the Local Study Team/Local Study Associate Director to ensure that study start-up activities and milestones are achieved in a timely and efficient manner
Typical Accountabilities:
Contribute to ensure that clinical and operational feasibility assessment of potential studies is performed to the highest quality.
Accountable for study start-up and regulatory maintenance being in charge with collection, preparation, review and tracking of documents for the application process;
Accountable for submission of proper application/documents to Regulatory Authorities and/or IEC/IRB during start-up period.
Actively participates in Local Study Team (LST) meetings.
Update CTMS and other systems with data from study sites as per required timelines during the start-up period.
Follow up on outstanding actions with study sites during start-up period to ensure resolution in a timely manner.
Ensure timely collection/uploading of essential documents into the eTMF in accordance with ICH-GCP, client SOPs and local requirements. Support QC checks performed by Trial Manager or delegate to ensure that all country and site level trial essential documents required by ICH-GCP prior to study start have been collected and verified for correctness, prior to setting sites ready to enroll, and in line with client SOPs.
Provide regular information to Line Managers at country level on study and planned study milestones/key issues during the start-up period.

Your profile

Bachelor’s Degree, preferably in life sciences.
Minimum of 5 years of experience in a Clinical Research environment, focusing on Start-Up.
Strong project management skills, with a deep understanding of regulatory and submission processes
Excellent written and verbal communication abilities.
Proven ability to work efficiently to tight deadlines and manage multiple priorities.

What ICON Can Offer You

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our Benefits Examples Include

Various annual leave entitlements
A range of health insurance offerings to suit you and your family’s needs.
Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
Life assurance
Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Are you a current ICON Employee? Please click here to apply

Apply About employer

More about this job

Responsibilities

Manage country-level clinical study start-up and site activation, including preparing, reviewing, tracking, and submitting regulatory and essential documents to authorities and ethics committees. Coordinate with study teams and sites, maintain study systems and performance metrics, follow up on outstanding actions, and ensure start-up milestones and compliance requirements are met.

Requirements

A bachelor’s degree, preferably in life sciences, and at least five years of clinical research experience focused on start-up are required. The role also calls for strong project management and regulatory submission knowledge, excellent communication, and the ability to meet tight deadlines while managing multiple priorities.

Skills

Clinical Study Start-Up
Site Activation
Regulatory Submissions
Regulatory Documentation
Project Management
Clinical Research
ICH-GCP Compliance
Regulatory Compliance
Essential Document Management
eTMF Management
CTMS Data Management
Site Performance Metrics
Clinical Feasibility Assessment
Quality Control
Stakeholder Collaboration
Deadline Management

Benefits

Annual Leave
Health Insurance
Retirement Planning
Employee Assistance Programme
Life Assurance
Childcare Vouchers
Bike Purchase Schemes
Discounted Gym Memberships
Subsidized Travel Passes
Health Assessments

Visa sponsorship

Not detected in the job text

Keywords

Clinical Research
Clinical Trials
Study Start-Up
Site Activation
Regulatory Affairs
Regulatory Submissions
Regulatory Authorities
IEC/IRB
ICH-GCP
Clinical Feasibility
Site Regulatory Documentation
Essential Documents
eTMF
CTMS
Site Performance Metrics
Local Study Team
Clinical Research Associates
Trial Management
Quality Control
Sponsor-Dedicated Model
Pharmaceutical Manufacturing

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