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Added 2 hours ago
S
Forward Deployed Engineer - Fintech
SweetTech
Montreal, QC
- Full-time
Take solutions from prototype to production with automated tests, operational monitoring, deployment plans, and support documentation.
Added 2 hours ago
S
Associate Forward Deployed Engineer - Fintech
SweetTech
Montreal, QC
- Full-time
…agent-generated changes, and verify correctness, security, and production readiness. You will validate your work with guidance and escalate uncertainty; experienced engineers retain…
Added 2 hours ago
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Marketing Engineer & Director of AEO
Notified
Toronto, ON
- Full-time
Design and manage production agents that support search visibility, content intelligence, technical QA, SERP analysis, AI answer monitoring, internal linking, schema validation, and…
Added 3 hours ago
J
Civil Engineer - Design and Project Management
JobsMedia.io
Montreal, QC
- Full-time
Civil Engineer – Urban Infrastructure Project Design and Management
Added 4 hours ago
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Principal Software Engineer
EngRadar
Kitamaat 2, BC
- Full-time
At Conga, we’ve built a community where our colleagues can thrive. Here you’ll find opportunities to innovate and support growth through individual and team development, all within an…
Added 6 hours ago
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Senior Data Center Network Engineer
K&K Global Talent Solutions INC.
Quebec, QC
- Full-time
We are seeking an expert-level Senior Data Center Network Engineer to own the design, deployment, implementation, and advanced escalation support of our enterprise-scale data center…
Added 9 hours ago
SM
RQ00813 – DevOps/Cloud Engineer – Senior
S M Software Solutions Inc
Toronto, ON
- Full-time
We are seeking a Senior DevOps/Cloud Engineer to support the Ontario Clinical Report Exchange (OCRE) project. The successful candidate will have extensive hands-on experience with AWS cloud…
Added 13 hours ago
H
Senior Electrical Engineer
HDR
Toronto, ON · Ottawa, ON · Richmond Hill, ON · Victoria, BC · Vancouver, BC · Calgary, AB
- Full-time
…to dynamic commercial environments, your work will directly support technological advancement, sustainability, and human experience. We bring together mechanical, electrical, structural,…
Added 13 hours ago
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Senior Mechanical Engineer
HDR
Calgary, AB
- Full-time
…to dynamic commercial environments, your work will directly support technological advancement, sustainability, and human experience. We bring together mechanical, electrical, structural,…
Added 13 hours ago
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Senior Project Manager
HDR
Calgary, AB
- Full-time
…to dynamic commercial environments, your work will directly support technological advancement, sustainability, and human experience. We bring together mechanical, electrical, structural,…
Added 15 hours ago
IP
Maintenance Supervisor
Intercity Packers Meat & Seafood
AB · Intercity Packers Edmonton-Alberta-ICP
- Full-time
Support the team during safety inspections and audits.
Added 17 hours ago
B
Principal Software Engineer
Broadcom
Ottawa, ON
- $114,400 to $183,000 CAD / year
- Full-time
As a Principal Software Engineer, you will design, develop, and deliver software and firmware for ultra-high-performance datacenter-scale solutions. We are looking for candidates who thrive…
Added 19 hours ago
BR
Senior Cloud Engineer (AWS)
BITS Recruiting
Toronto, ON
- Contract
…containerized applications, and cloud infrastructure operations. The engineer will support automated deployments, infrastructure provisioning, production troubleshooting, and secure,…
Added 19 hours ago
SM
RQ00813 – DevOps/Cloud Engineer – Senior
S M Software Solutions Inc
Toronto, ON
- Full-time
We are seeking a Senior DevOps/Cloud Engineer to support the Ontario Clinical Report Exchange (OCRE) project. The successful candidate will have extensive hands-on experience with AWS cloud…
Added 19 hours ago
SM
RQ00813 – DevOps/Cloud Engineer – Senior
S M Software Solutions Inc
Toronto, ON
- Full-time
We are seeking a Senior DevOps/Cloud Engineer to support the Ontario Clinical Report Exchange (OCRE) project. The successful candidate will have extensive hands-on experience with AWS cloud…
Added 19 hours ago
SM
RQ00813 – DevOps/Cloud Engineer – Senior
S M Software Solutions Inc
Toronto, ON
- Full-time
We are seeking a Senior DevOps/Cloud Engineer to support the Ontario Clinical Report Exchange (OCRE) project. The successful candidate will have extensive hands-on experience with AWS cloud…
Added 20 hours ago
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Mechanical BIM Designer
HDR
Toronto, ON
- Full-time
…to dynamic commercial environments, your work will directly support technological advancement, sustainability, and human experience. We bring together mechanical, electrical, structural,…
Added 21 hours ago
PP
Estimator - Civil Construction
Park Paving Ltd.
AB · Edmonton, AB
- Full-time
The right candidate will understand how civil construction work is built, what drives production, where risk exists, and how strong estimating decisions contribute to successful project…
Added 21 hours ago
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PD Software for Service
Husky Technologies
Bolton, ON
- Full-time
…attracted to bold goals, believe in uncompromising honesty, support mutual respect, care about environmental responsibility, have a passion for excellence and a desire to make a positive…
Added 21 hours ago
HT
PD Service - Mechanical
Husky Technologies
Bolton, ON
- Full-time
…attracted to bold goals, believe in uncompromising honesty, support mutual respect, care about environmental responsibility, have a passion for excellence and a desire to make a positive…
Added 22 hours ago
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Project Manager - Environmental Assessment
HDR
Toronto, ON
- Full-time
…transportation ports and marine infrastructure, your work will directly support economic vitality, public safety, sustainable and resilient communities and quality of life. We bring…
Added 22 hours ago
O
Cloud Network Architect
OnX
Toronto, ON · Greater Toronto Area, Canada
- Full-time
Reporting to the Manager, Network Operations, the Network Engineer plays a lead role in the Network Administration team responsible for the design, implementation, and operational support…
Added 22 hours ago
AM
Supplier Quality Engineer
Ampco Manufacturers Inc.
Coquitlam, BC
- $60,000 to $80,000 CAD / year
- Full-time
Provide support with NCs, identifying root causes of problems in the production process; recommend and/or implement corrective actions.
Added 23 hours ago
A
AI/ML Systems Engineer
Actalent
Ottawa, ON
- $55 to $79 CAD / hour
- Contract
…vehicle diagnostics and cloud-based observability. As a Systems Engineer, you will help define, integrate, and mature intelligent diagnostic workflows that connect embedded vehicle…
Added 23 hours ago
AS
Robotics Engineer
ARV Solutions
Cambridge, ON
- Full-time
…services for automated, robotic, and machine vision equipped production machinery. The company focuses on helping clients design, optimize, and deploy advanced automation systems that…

Molagri

Sr. Research Associate, Yeast Expression and VLP Production

Toronto, ON, Canada

$85,000 to $105,000 USD / year · Full-time

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Job details

Pay: $85,000 to $105,000 USD / year
Job type: Full-time
Posting language: English
Posted: Oct 6, 2026

Original job description

We are seeking a hands-on research associate to produce engineered VLPs in yeast and build production, purification, QC, and stability workflows.

You will help build Molagri’s yeast VLP production workflows. This role will focus on expressing engineered VLPs in yeast, improving yield and recovery, purifying particles, running routine QC, and screening storage conditions that preserve particle integrity and payload quality.

You will work closely with our virology and protein biochemistry teams to produce purified VLP material for characterization, insect-cell assays, and insect bioassays.

You will:

Engineer strains of yeast to accommodate efficient cell growth and VLP yields at manufacturing scale.
Work closely with viral and biochemistry teams to genetically modify yeast strains to test new VLP variants in a timely manner.
Transform yeast with VLP expression constructs and screen clones for their expression, yield, and particle quality.
Produce VLPs in shake flasks and small-scale bioreactors.
Test and optimize production conditions such as growth media, induction strategy, temperature, harvest time, and other process variables.
Run harvest, lysis or clarification, purification, buffer-exchange, and concentration workflows.
Run routine QC assays for expression, particle assembly, purity, aggregation, RNA packaging, and RNA integrity.
Support stability screens across pH, salt, excipients, temperature, freeze-thaw, and storage conditions.
Troubleshoot low-yield expression, poor recovery, particle instability, aggregation, RNA loss, and inconsistent QC results.
Maintain SOPs, batch records, assay records, and sample inventories.

What You Bring

BSc or MS in biochemistry, molecular biology, microbiology, biochemical engineering, biotechnology, or a related field.
Hands-on experience expressing recombinant proteins, VLPs, or other biological products in yeast or microbial systems.
Experience with yeast transformation, clone screening, shake-flask expression, and small-scale fermentation or bioreactor runs.
Experience with protein and/or particle purification methods involved in the preparation of samples and downstream protocols such as chromatography, filtration.
Working knowledge of routine protein, RNA, or particle QC methods such as SDS-PAGE, Western blot, ELISA, qPCR, HPLC/SEC, DLS, or plate-based activity assays.
Precise/meticulous bench technique and the ability to reproducibly run many small production and QC experiments.
Strong recordkeeping skills, including clear batch recording, assay notes, sample tracking, and SOP updates.
Ability to troubleshoot production workflows and communicate results clearly to scientists across virology, protein biochemistry, and insect biology.
Excitement to work at the bench in a small team where production workflows are still being built.
Self-starter with a drive to grow with their role alongside the company’s trajectory.

What We Value

Molagri is a small team building a novel bioinsecticide platform. We value scientists who design rigorous experiments, think creatively when the obvious approach fails, communicate clearly, and treat their teammates with kindness and respect. The right person for this role will be hands-on, hard-working, intellectually honest, and excited to help build a platform from first principles.

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More about this job

Responsibilities

Engineer and screen yeast strains for VLP production, optimize expression and small-scale production conditions, and purify particles for downstream research. Run routine quality-control and stability assays, troubleshoot production issues, and maintain accurate SOPs, batch records, assay records, and sample inventories.

Requirements

A BSc or MS in a relevant life-science or engineering field and hands-on experience expressing recombinant proteins, VLPs, or other biological products in yeast or microbial systems are required. Candidates should have experience with yeast transformation, clone screening, small-scale fermentation, purification, routine protein/RNA/particle QC, meticulous recordkeeping, and cross-functional communication.

Skills

Yeast Transformation
Yeast Strain Engineering
VLP Expression
Clone Screening
Shake-Flask Expression
Small-Scale Fermentation
Bioreactor Operation
Protein and Particle Purification
Chromatography
Filtration
Protein and RNA Quality Control
SDS-PAGE
Western Blot
ELISA
qPCR
Stability Screening

Benefits

Equity

Visa sponsorship

Not detected in the job text

Keywords

Yeast Expression
Virus-Like Particles
VLP Production
Yeast Strain Engineering
Yeast Transformation
Clone Screening
Shake-Flask Production
Small-Scale Bioreactors
Fermentation
Growth Media Optimization
Induction Strategy
Harvesting
Cell Lysis
Clarification
Particle Purification
Buffer Exchange
Concentration
SDS-PAGE
Western Blot
ELISA
qPCR
HPLC/SEC
Dynamic Light Scattering
RNA Packaging
RNA Integrity
Stability Screening
Batch Records
Standard Operating Procedures
Bioinsecticide

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