Software development jobs in Canada

Explore software development jobs in Canada. Choose a role or place to find work that fits.

Counted Sep 29, 2026

Hiring at a glance

View jobs

Open jobs: 3,995
Employers: 1,450

Advertised starting pay

Average starting payCAD / year: $115,196Across 457 listings
Average starting payUSD / year: $139,540Across 111 listings
Average starting payCAD / hour: $52.03Across 63 listings

Employer-advertised starting pay, not employee salaries. Currencies and pay periods stay separate.

Where work happens

Remote: 10%405 listings
Hybrid: 40%1,614 listings
On-site: 49%1,939 listings

Not specified: 1% (37 listings)

Employers hiring include Amazon (119), Genetec (67), Citi (39).

Sources & calculation notes

These figures describe the listings on this role page at the date shown, not the whole job market. Listings can change.

Employer-listed minimums from at least 10 listings per currency and pay period. These are advertised starting amounts, not employee salaries. Jobs without a minimum and unusual amounts are excluded.

Hybrid and on-site classifications may be inferred from descriptions. Check the original ad. How we count

Software development jobs in Canada

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Added 11 days ago
Senior Site Reliability Engineer (SRE) – CloudVision as a Service (CVaaS)
Arista Networks
Vancouver, BC
Full-time
…advancements in cloud computing, artificial intelligence, and software-defined networking to provide our clients with a competitive edge in an increasingly interconnected world. Our…
Added 11 days ago
Senior Software Engineer, Agent Gateway
Okta
Toronto, ON
$136,000 to $187,000 CAD / year
Full-time
Added 11 days ago
Java Full Stack Developer
Hirematic Talent Solutions
Montreal, QC
$40 to $45 CAD / hour
Contract
Full-stack development across back-end and front-end, including:
Added 11 days ago
Senior Software Developer
Nanometrics Inc
Ottawa, ON
Added 12 days ago
Senior Software Engineer, Operations
Sun Life
Toronto, ON · Waterloo, ON · Sun Life Waterloo King
Full-time
Added 11 days ago
Software Developer - Dev Ops
Aplin
Winnipeg, MB
Full-time
Support the DevOps team with ongoing software development and enhancement projects
Added 12 days ago
Principal Software Developer
Open Text Corporation
Richmond Hill, ON
Added 11 days ago
Cloud Engineer
CDW Canada
Vancouver, BC · Greater Vancouver, BC
Contract
Added 12 days ago
Software Developer Senior Specialist (AI-First Engineering)
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Toronto, ON
Full-time
As a Senior Specialist - Software Development reporting to the Head of Market Data and AI Enablement, you'll play a key hands-on role in designing, developing, troubleshooting, and…
Added 11 days ago
Full Stack Developer
RBC
Toronto, ON
Full-time
Front-end development - Build responsive, user-friendly web interfaces using Angular and TypeScript
Added 11 days ago
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Montreal, QC
Contract
Lead design and development of scalable Java/Spring Boot microservices and event-driven solutions.
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Application Architect (ID#5234)
New Value Solutions
Vancouver, BC · Greater Vancouver, BC
Full-time
New Value Solutions, a national IT consulting company, is seeking an Application Architect to lead the design and development of enterprise-scale software systems. The Application Architect…
Added 12 days ago
Full Stack Developer (Azure Databricks, Oracle, Firco)
CIBC
Toronto, ON
Full-time
Added 12 days ago
Software Engineer (S/W Dev & AI Solutions)
Synpulse
Toronto, ON
Added 12 days ago
Software Dev Engineer, AFFS - ARS (Amortization Runtime Subledger)
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Vancouver, BC
Full-time
As a Software Development Engineer, you'll design massively scalable distributed
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Senior Systems Architect
Euna Solutions
ON · Oakville, Ontario
Full-time
Added 12 days ago
Senior Systems Architect
Euna Solutions
ON · Oakville, Ontario
Full-time
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Programmer Analyst, System and infrastructure operations, maintenance and development
Desjardins
Levis, QC · Montreal, QC
Full-time
As a systems and infrastructure development, operations and maintenance programmer analyst, you participate in IT efficiency and quality by analyzing, designing, configuring, developing,…
Added 12 days ago
Quality Assurance Software Engineer - Contract Role
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AB
Full-time
Join our dynamic team as a QA Software Engineer! In this role you’ll be developing and executing comprehensive automated test plans and cases for all software projects. You’ll increase…
Added 12 days ago
Senior Siebel Software Developer – Siebel, EAI/EIM, AEM & BI Reporting
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Toronto, ON
Contract
Seeking 10+ years of hands-on Siebel development experience covering technical configuration, design, development, customization, and integration.
Added 12 days ago
Software Developer, React Native - Hybrid
Pelmorex
Oakville, ON
Full-time
Added 12 days ago
Software Developer, React Native - Hybrid
Pelmorex
Oakville, ON
Full-time
Added 12 days ago
DevOps Software Engineer - ITS4
Minnesota Direct Care and Treatment
Saint-Paul, NB · St.-Paul, NB
Full-time
Added 12 days ago
Senior Cloud Engineer - Google Firebase
BDO Canada
Toronto, ON
Full-time
Added 12 days ago
Sr Java Backend Developer
Tekgence Inc
Toronto, ON
Contract

ProteinQure Inc

Research Software Engineer

Toronto, ON, Canada

Pay: $120,000 to $150,000 CAD / year
Experience: 3-5 years of software development experience
Posting language: English
Posted: Sep 16, 2026

Apply About employer

Applications open in a new tab.

Original job description

About ProteinQure

At ProteinQure, we have built the best computational platform for peptides that target extracellular targets. Our mission is to help to create a world where drugs are engineered, not discovered. We work on treatments for cancer and other indications while also partnering with industry leaders in drug discovery to generate novel therapeutics outside of the conventional chemical space.

Our technology combines computational biophysical models with statistical and machine learning approaches to enable us to search across vast spaces of protein therapeutics. We have worked with three of the top 25 pharma companies and have validated our tools on multiple targets.

We also have multiple internal programs, the most advanced being a First-in-Class peptide drug conjugate for TNBC, which is in a Phase 1 clinical trial including the best sites in North America. A second clinical program is expected within 3 years. Our other internal programs focus on using peptides as delivery vehicles for therapeutic payloads such as radioisotopes and siRNA.

Position: Research Software Engineer

Reports to: Head of Engineering

Status: Permanent

Expected Compensation Range: $120,000 to $150,000 CAD annually, based on skills, qualifications, and relevant experience.

The Research Software Engineer is responsible for developing, maintaining, and supporting the software tools and computational workflows that enable ProteinQure’s drug discovery research. Working closely with scientists and engineers, they translate research needs into reliable, reproducible software, troubleshoot technical issues, and improve the performance and usability of the computational platform. The role combines hands-on software development with technical support for scientific users, along with ownership of scoped projects and contributions to testing, documentation, and shared engineering practices.

This job posting is to fill a new position. Artificial intelligence may be used to assist in the initial screening of resumes for this position. This process is supervised by a human, and hiring decisions are not made solely by artificial intelligence.

Key responsibilities include:

Development, maintenance, and support for scientific computational workflows.
Development of computational tools for protein property prediction and optimization
Scoping computational resource requirements for internal and external research projects
Collection of product requirements from scientists and translation into technical specifications
Supporting development of machine learning models
Participating in code reviews and shared engineering practices; taking ownership of scoped improvements from requirements through deployment and ongoing support.

Required Knowledge, skills and abilities

3-5 years of software development experience
Proficiency in Python and experience maintaining software used by others, including debugging, testing, and dependency management.
Experience using AI-assisted development tools, with independent review, testing, and validation of generated code and appropriate handling of confidential information.
Familiarity with Linux environments, shell scripting, and troubleshooting software execution issues.
Ability to prioritize development tasks alongside support requests, communicate tradeoffs, and recognize when to seek guidance.
[Nice-to-have] Devops experience. Kubernetes experience. Experience with computer hardware / on-prem servers.
[Nice-to-have] Experience in cell, molecular or protein biology.
Excellent English communications skills, both verbal and written
Legally able to work in Canada

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More about this job

Responsibilities

The Research Software Engineer will develop, maintain, and support computational workflows and software tools for drug discovery research. They will collaborate with scientists to translate research needs into technical specifications and ensure the reliability and performance of the computational platform.

Requirements

Candidates must have 3-5 years of software development experience with proficiency in Python and Linux environments. Familiarity with AI-assisted development tools and experience in scientific or computational research settings is highly valued.

Skills

Python
Software Development
Linux
Shell Scripting
Debugging
Testing
Dependency Management
Machine Learning
Computational Biology
Protein Engineering
Workflow Automation
Technical Documentation
Code Review
Devops
Kubernetes

Visa sponsorship

Not detected in the job text

Keywords

Research Software Engineer
Python
Computational Biology
Drug Discovery
Machine Learning
Linux
Shell Scripting
Devops
Kubernetes
Protein Therapeutics
Biophysical Models
Software Development
Workflow Automation
Debugging
Testing
Dependency Management
Technical Specifications
Code Review
Peptide Drug Conjugate
Molecular Biology
Cell Biology
Computational Platform
Data Analysis
Software Engineering
Biotechnology

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