Software development jobs in Toronto, ON and nearby

Software development jobs within 25 km of Toronto, ON, Canada. Nearby towns and cities are included. Distances are straight-line, not driving distances.

Counted Oct 5, 2026

Hiring at a glance

View jobs

Open jobs: 1,573
Employers: 556

Advertised starting pay

Average starting payCAD / year: $119,922Across 161 listings
Average starting payUSD / year: $146,848Across 46 listings
Average starting payCAD / hour: $60.27Across 30 listings

Employer-advertised starting pay, not employee salaries. Currencies and pay periods stay separate.

Where work happens

Remote: 0%0 listings
Hybrid: 49%767 listings
On-site: 50%789 listings

Not specified: 1% (17 listings)

Employers hiring include Amazon (49), S M Software Solutions Inc (48), Okta (44).

Sources & calculation notes

These figures describe the listings on this role page at the date shown, not the whole job market. Listings can change.

Employer-listed minimums from at least 10 listings per currency and pay period. These are advertised starting amounts, not employee salaries. Jobs without a minimum and unusual amounts are excluded.

Hybrid and on-site classifications may be inferred from descriptions. Check the original ad. How we count

Software development jobs in Toronto, ON and nearby

Within 25 km

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Added 5 months ago
HC
Senior Software Developer – Big Data (C++/Rust)
Huawei Canada
Markham, ON
- Full-time
Huawei Canada has an immediate 12-month contract opening for a Software Developer.
Added 16 days ago
I
Software Developer 1, Canada Tax Content
Intuit
Toronto, ON
- Full-time
The Canada Tax Content team is looking for a motivated Software Developer 1 to help build and maintain Canada's leading tax products. This is an entry-level, growth-oriented role for an…
Added 20 days ago
P
Senior Software Engineer (Conductor)
PocketHealth
Toronto, ON
- Full-time
Added 16 days ago
M
Senior Software Engineer- Applied AI
Morningstar
Toronto, ON
- Full-time
Added 17 days ago
R
Senior Back-End Developer
RBC
Toronto, ON
- Full-time
Added 16 days ago
A
Software Development Engineer, Amazon Customer Service
Amazon
Toronto, ON
- Full-time
Added 17 days ago
A
Software Engineering Co-op - Winter 2027
Achievers
Toronto, ON
- $28 to $40 CAD / hour
Added 16 days ago
S
Connect Systems Programmer
Swoon
Toronto, ON
- $85,000 to $95,000 CAD / year
- Full-time
Added 16 days ago
ZG
Full Stack Developer
ZAPCOM GROUP INC
Toronto, ON
- Full-time
Added 1 month ago
W
Senior / Staff Software Engineer, ML-based Controls
Waabi
Toronto, ON
- $241,000 to $320,000 USD / year
- Full-time
Added 17 days ago
GM
Software Engineer, Simulation Scalability - Sim RIM (Release and Incident Management) Focus
General Motors
Markham, ON
- Full-time
Added 17 days ago
RB
Senior Back-End Developer
Royal Bank of Canada
Toronto, ON
- Full-time
Added 17 days ago
Backend Engineer, Consumer
HelloFresh
Toronto, ON
Added 17 days ago
Software Development Engineer, Amazon Customer Service
Amazon
Toronto, ON
Added 17 days ago
M
Senior software engineer: Applied AI
Morningstar
Toronto, ON
- Full-time
Added 17 days ago
P
Member of Technical Staff (General Software Engineer, Infrastructure)
Perplexity
Toronto, ON
- $220,000 to $405,000 USD / year
- Full-time
Added 17 days ago
KC
Senior Embedded Software Designer
Kepler Communications
Toronto, ON
- Full-time
Added 17 days ago
SS
Senior Azure Cloud Administrator
Sienna Senior Living
Markham, ON
- Full-time
Added 17 days ago
PH
Sr. Software Developer
Propel Holdings
Toronto, ON
- Full-time
Added 17 days ago
GS
Software Engineer II
Guidewire Software
Toronto, ON · Mississauga, ON
- Full-time
Guidewire’s development team is looking for a smart, proactive, and results-oriented Software Engineer II to build elegant solutions for the property & casualty insurance industry’s…
Added 17 days ago
FS
Senior Software Engineer (Front End / Integration), Hospitality Operations Technology
Four Seasons Hotels and Resorts
Toronto, ON
- Full-time
Added 17 days ago
ZG
Java Software Developer
ZAPCOM GROUP INC
Toronto, ON
- Full-time
Added 17 days ago
T
Java Software Engineer
Tekshapers
Mississauga, ON
- Full-time
Added 17 days ago
SL
Student, Full Stack Developer
Sun Life
Toronto, ON
- Full-time
Added 17 days ago
I
Staff Software Developer, Canada Tax Content
Intuit
Toronto, ON
- Full-time
The Canada Tax Content team is looking for a highly motivated, innovative Staff Software Developer to help build and maintain Canada's leading tax products. You'll work with a diverse team…

ProteinQure

Research Software Engineer

Toronto, ON, Canada

$120,000 to $150,000 CAD / year · Full-time

Apply About employer

Applications open in a new tab.

Job details

Pay: $120,000 to $150,000 CAD / year
Job type: Full-time
Apply by: Mar 15, 2027
Experience: 3-5 years of software development experience
Posting language: English
Posted: Sep 16, 2026

Original job description

About ProteinQure

At ProteinQure, we have built the best computational platform for peptides that target extracellular targets. Our mission is to help to create a world where drugs are engineered, not discovered. We work on treatments for cancer and other indications while also partnering with industry leaders in drug discovery to generate novel therapeutics outside of the conventional chemical space.

Our technology combines computational biophysical models with statistical and machine learning approaches to enable us to search across vast spaces of protein therapeutics. We have worked with three of the top 25 pharma companies and have validated our tools on multiple targets.

We also have multiple internal programs, the most advanced being a First-in-Class peptide drug conjugate for TNBC, which is in a Phase 1 clinical trial including the best sites in North America. A second clinical program is expected within 3 years. Our other internal programs focus on using peptides as delivery vehicles for therapeutic payloads such as radioisotopes and siRNA.

Position: Research Software Engineer

Reports to: Head of Engineering

Status: Permanent

Expected Compensation Range: $120,000 to $150,000 CAD annually, based on skills, qualifications, and relevant experience.

The Research Software Engineer is responsible for developing, maintaining, and supporting the software tools and computational workflows that enable ProteinQure’s drug discovery research. Working closely with scientists and engineers, they translate research needs into reliable, reproducible software, troubleshoot technical issues, and improve the performance and usability of the computational platform. The role combines hands-on software development with technical support for scientific users, along with ownership of scoped projects and contributions to testing, documentation, and shared engineering practices.

This job posting is to fill a new position. Artificial intelligence may be used to assist in the initial screening of resumes for this position. This process is supervised by a human, and hiring decisions are not made solely by artificial intelligence.

Key Responsibilities Include

Development, maintenance, and support for scientific computational workflows.
Development of computational tools for protein property prediction and optimization
Scoping computational resource requirements for internal and external research projects
Collection of product requirements from scientists and translation into technical specifications
Supporting development of machine learning models
Participating in code reviews and shared engineering practices; taking ownership of scoped improvements from requirements through deployment and ongoing support.

Required Knowledge, Skills And Abilities

3-5 years of software development experience
Proficiency in Python and experience maintaining software used by others, including debugging, testing, and dependency management.
Experience using AI-assisted development tools, with independent review, testing, and validation of generated code and appropriate handling of confidential information.
Familiarity with Linux environments, shell scripting, and troubleshooting software execution issues.
Ability to prioritize development tasks alongside support requests, communicate tradeoffs, and recognize when to seek guidance.
[Nice-to-have] Devops experience. Kubernetes experience. Experience with computer hardware / on-prem servers.
[Nice-to-have] Experience in cell, molecular or protein biology.
Excellent English communications skills, both verbal and written
Legally able to work in Canada

Apply About employer

More about this job

Responsibilities

The Research Software Engineer will develop, maintain, and support computational workflows and tools for drug discovery research. They will collaborate with scientists to translate research requirements into reliable software and contribute to shared engineering practices.

Requirements

Candidates must have 3-5 years of software development experience with proficiency in Python and Linux environments. Experience with AI-assisted development tools and the ability to troubleshoot software execution issues are also required.

Skills

Python
Software development
Linux
Shell scripting
Debugging
Testing
Dependency management
Computational workflows
Machine learning
Protein property prediction
Code reviews
Technical specifications
Kubernetes
Devops
Molecular biology
Protein biology

Visa sponsorship

Not detected in the job text

Keywords

Research Software Engineer
Computational platform
Peptides
Drug discovery
Biophysical models
Machine learning
Python
Linux
Shell scripting
Kubernetes
Devops
Protein biology
Molecular biology
Software development
Computational workflows
Code reviews
Debugging
Testing
Dependency management
Biotechnology
Therapeutics
Clinical trial
Technical specifications
AI-assisted development

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