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Added 12 mins ago
AH
Registered Nurse
Alberta Health Services
Three Hills, AB
- Part-time
…fast-paced environment in Acute Care, Emergency and Labour & Delivery. This position will challenge your ability to balance varying patient acuity levels and priorities within a team…
Added 12 mins ago
AH
Senior IAM Architect
Alberta Health Services
Calgary, AB · Greater Calgary Metropolitan Area
- Full-time
Added 1 hour ago
LH
Director, Technology Delivery and Enablement
Lifemark Health Group
Brampton, ON
- $130,000 to $160,000 CAD / year
- Full-time
This is a hybrid position, with four days per week in the office and one day remote
Added 1 hour ago
CS
Instructor, Video Game Coding and Game Design (Calgary)
Circuit Stream
Calgary, AB
- $1,650 CAD / week
- Contract
…and excited to help young people discover where theirs might lead, you’ll thrive…
Added 1 hour ago
TC
Senior AI Solutions Lead Resource
ThirdEye CyberSecurity
Regina, SK
- Contract
Must have a minimum of five (5) years experience delivering software solutions; · Must have a minimum of two (2) years experience developing AI solutions;
Added 2 hours ago
T
Head of IoT Services (12 Month Maternity Cover)
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London, ON
- $99,000 to $123,000 CAD / year
- Full-time
We are looking for a Head of IoT Services to build and lead the organization that sits behind every successful Trackunit deployment. When a customer connects their first device, activates…
Added 3 hours ago
FR
Project Manager
Foresight Recruitment Group
Toronto, ON · Greater Toronto Area, Canada
- Full-time
Our client is an established general contractor with a strong pipeline of work and is looking for a Project Manager to lead construction projects from preconstruction through to completion.
Added 4 hours ago
H
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Kelowna, BC
- Full-time
The Service Manager will lead day-to-day electrical Service operations across Kelowna and Kamloops, coordinating service delivery and strengthening collaboration across teams, departments,…
Added 4 hours ago
S
BIM Coordinator – HaLRT
SYSTRA
Toronto, ON
- $70,000 to $100,000 CAD / year
- Full-time
Organize and lead BIM coordination meetings and reviews; document technical issues, decisions, and follow-up actions.
Added 4 hours ago
UO
Lab Instructor, Bioengineering
University of Waterloo
Waterloo, ON · Douglas Wright Engineering Blg
- Full-time
…Instructor – Bioengineering provides instruction, guidance, and technical assistance for courses with labs and for design-project and workshop courses, and is responsible for ensuring safe…
Added 4 hours ago
CO
Temporary Technical Lead (Housing Accelerator Fund) Up to 18 Months
City of Saint John
Saint John, NB
- Temporary
A minimum of three (3) years of experience in project management or municipal project delivery, with an emphasis on process improvement and operational efficiency, is required.
Added 4 hours ago
L
AI/ML Engineer
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- Full-time
…running, training, and other athletic pursuits. Setting the bar in technical fabrics and functional design, we create transformational products and experiences that support people in…
Added 4 hours ago
Solution Delivery Manager
Rogers Communications
Toronto, ON · Brampton, ON · Calgary, AB
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Added 5 hours ago
C
Vice-président(e), centres mondiaux de prestation
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- Full-time
Lead initiatives to strengthen governance maturity, including quality, risk management, security and service delivery standards.
Added 5 hours ago
C
Organizational Change Manager
CGI
Halifax, NS
- Full-time
This role is hybrid and requires you to be at our client's and/or the CGI Halifax office a minimum of 3 days per week - subject to change at any time
Added 5 hours ago
C
Senior Software Developer- Cloud & Data Platforms
CGI
Halifax, NS
- Full-time
Previous technical leadership or team lead experience.
Added 5 hours ago
VB
Sr. Manager of Projects Controls - Canada
Vale Base Metals
Toronto, ON
- Full-time
…Metals' Canadian studies portfolio. The role serves as the technical leader for the estimating and cost control discipline in Canada and is accountable for the methodologies, standards,…
Added 5 hours ago
KD
Directeur stratégie commerciale et gestion de la croissance du revenu/ Manager, Trade Strategy and Revenue Growth Management
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Montreal, QC
- Full-time
Added 5 hours ago
P&
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Mirabel, QC
- Full-time
Added 5 hours ago
S
Regional Delivery Manager
Skip
Toronto, ON
- Full-time
The Regional Delivery Manager is accountable for achieving network KPI & budget targets for the regions they are responsible for. You will be expected to investigate the root cause of…
Added 5 hours ago
A
Senior Study Manager
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Burnaby, BC
- Full-time
…environments. Delivering innovative, value-add consulting, project delivery, asset operations and maintenance solutions is what we do. From 22 offices in 9 countries, with projects in over…
Added 6 hours ago
S
Nurse, Clinical Informatics Specialist
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Vancouver, BC
- Full-time
…with other subject matter experts to support development and delivery of education for end users to enhance adoption, including use of clinical decision support tools within the clinical…
Added 6 hours ago
CS
Youth Experience Assistant (Calgary)
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Calgary, AB
- $20 CAD / hour
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…and excited to help young people discover where theirs might lead, you’ll thrive…
Added 6 hours ago
IS
DevOps & Cloud Infrastructure Engineer
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Markham, ON
- Full-time
Integrate security checks into delivery workflows and coordinate responses to technical risks.
Added 6 hours ago
A
Senior Systems Analyst - DocuSign Platform
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Toronto, ON
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Work Model: Hybrid - 3 days per week in office

X-Chem

Assistant Scientist - Biophysics / SPR

Nemiscau, QC, Canada

Apply on careers.xchemrx.com About employer

Applications open in a new tab.

Job details

Apply by: Jan 1, 2027
Posting language: English
Posted: Oct 29, 2026

Original job description

At X-Chem, it is our mission to leverage the world’s leading drug discovery platform to help create molecules that will improve human health. At X-Chem, we do more than screen compounds. We help you make confident decisions that move science forward. Our integrated platform combines DNA-encoded libraries, medicinal chemistry, advanced modeling and proprietary AI into a powerful and precise discovery engine. Everything is connected through Chemomics, our approach to unlocking value from every data point. Whether you’re exploring a new target or refining a lead, we help you discover high-quality molecules with greater speed, insight and control.

This position will support the development and execution of biochemical and biophysical assays, with a particular focus on Surface Plasmon Resonance (SPR). The successful candidate will contribute to assay development, optimization, execution, data analysis, troubleshooting, and reporting in support of drug discovery programs. Previous SPR or Biacore experience is considered an asset; candidates with strong biochemical or biophysical assay experience and an interest in developing SPR expertise will also be considered. The ideal candidate has 1 to 3 years of laboratory experience

This position will be located at X-Chem’s offices in Montreal, QC Canada.

Job Responsibilities:

Perform and support biochemical and biophysical assay activities, including SPR-based experiments.
Execute established protocols and experimental plans, including repeat analyses, troubleshooting, and investigation-related activities.
Support assay and method development, optimization, verification, validation, and transfer activities.
Prepare buffers, reagents, samples, and dilution series accurately and reproducibly, including pH adjustment and verification.
Maintain and complete accurately the laboratory documentation.
Ensure data integrity, and accuracy of all generated, analyzed, and reported results.
Maintain laboratory equipment and coordinate routine instrument checks, troubleshooting, and service activities as required.
Follow laboratory safety requirements, established procedures, and good scientific practices.

Skills and Qualifications:

BSc in Biochemistry, Biophysics, Biology, Biotechnology, Chemistry, or related scientific discipline with 1 to 3 years of relevant hands-on laboratory experience.
Relevant hands-on laboratory experience with biochemical, biophysical, or related life-science assays.
Strong pipetting skills and experience preparing buffers and solutions, including the use of a pH meter.
General understanding of protein chemistry, biomolecular interactions, and reaction and/or enzyme kinetics.
Experience executing laboratory protocols independently with strong attention to detail and reproducibility.
Ability to analyze, interpret, and troubleshoot experimental data.
Experience supporting method development, optimization, verification, validation, and/or method transfer.
Strong understanding of laboratory documentation, data integrity, traceability, and scientific reproducibility.
General knowledge of laboratory safety, chemical handling, and good laboratory practices.
Strong organizational skills and ability to manage multiple experiments or projects concurrently.
Good written and verbal communication skills and ability to work effectively within multidisciplinary project teams.

Preferred Qualifications

SPR experience is preferred but is not a mandatory requirement for this position.
Understanding of biomolecular interaction kinetics and affinity, including association rate, dissociation rate, and equilibrium binding constants.
Experience interpreting binding curves or sensorgrams and evaluating assay quality.
Experience in a drug discovery, biotechnology, pharmaceutical, or CRO environment.
Experience preparing technical reports and presenting scientific data to internal project teams.

The company cooperates with its customers, partners and colleagues outside Quebec for the research and development of medical products based on the identification and optimization of small molecules enabling the development of specific drugs. Interaction with colleagues and partners outside Quebec, notably in Budapest and Waltham, is constant. Consequently, knowledge of English is required for this unique and specialized position. Knowledge of French is required for positions permanently located in Quebec, so that the incumbent can communicate as needed with colleagues, customers and partners in Quebec. French-language training will be offered to any incumbent of a permanent position in Quebec who does not have a good knowledge of French.

Why join X-Chem?

Our scientists innovate beyond reported chemistry while focusing on delivery. We all share a passion for staying at the forefront of computational, cheminformatics, medicinal and synthetic chemistry. To drive innovation, we acknowledge the importance of intelligent risk-taking, open-mindedness and initiative. We encourage creativity in an informal environment and recognize everyone’s contribution as part of a team to work together toward a common vision.

What are the benefits joining us?

We are focused on the development and career progression of our people to reach their full potential through workshops, training courses and mentor guidance. X-Chem offers competitive compensation (salary and performance incentive) and interesting benefits package. Benefits we offer include: Medical, Dental, STD/LTD and Life Insurance, Retirement Plan with employer match; paid vacations based on local policy; casual dress, vision care including prescription safety glasses, training sessions and workshops, social hours and team-building company events.

EEO Statement

X-Chem is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.

Apply on careers.xchemrx.com About employer

More about this job

Responsibilities

The Assistant Scientist will support the development, execution, and optimization of biochemical and biophysical assays, with a focus on Surface Plasmon Resonance (SPR). Responsibilities include maintaining laboratory documentation, ensuring data integrity, and managing routine instrument maintenance and troubleshooting.

Requirements

Candidates must hold a BSc in a relevant scientific discipline and possess 1 to 3 years of hands-on laboratory experience. Strong skills in assay execution, buffer preparation, and data interpretation are required, along with the ability to work effectively in a multidisciplinary team.

Skills

Surface Plasmon Resonance
Biacore
Biochemical assays
Biophysical assays
Assay development
Data analysis
Troubleshooting
Protein chemistry
Biomolecular interactions
Enzyme kinetics
Pipetting
Buffer preparation
Laboratory documentation
Data integrity
Scientific reproducibility
Method validation

Benefits

Medical insurance
Dental insurance
Short-term disability insurance
Long-term disability insurance
Life insurance
Retirement plan
Paid vacations
Vision care
Prescription safety glasses
Training sessions
Workshops
Social hours
Team-building events

Visa sponsorship

Not detected in the job text

Keywords

Surface Plasmon Resonance
SPR
Biacore
Drug discovery
Biochemistry
Biophysics
Assay development
Protein chemistry
Biomolecular interactions
Enzyme kinetics
Data integrity
Laboratory safety
Method validation
Small molecules
Biotechnology
Pharmaceutical
CRO
Technical reporting
Pipetting
Buffer preparation
pH meter
Reproducibility
Multidisciplinary teams
Scientific research
Laboratory documentation

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Work requirements

Jobs in Canada