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Added 5 hours ago
SM
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SM
Senior Director, Clinical Trials Performance & Head of Operations, SPHERE CRO
St. Michael's Hospital
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- Full-time
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St. Michael's Hospital

Senior Director, Clinical Trials Performance & Head of Operations, SPHERE CRO

Toronto, ON, Canada

Full-time

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Job details

Job type: Full-time
Apply by: Dec 13, 2026
Posting language: English
Posted: Nov 13, 2026

Original job description

CONTACT INFORMATION

If you are interested in being considered for this exciting and impactful opportunity,

please submit your cover letter and current resume by email to Chris Sawyer, Senior Consultant, at chris.sawyer@lhhknightsbridge.com .

THE ORGANIZATION

Unity Health Toronto is one of Canada’s largest Catholic healthcare networks serving patients, residents and clients across the full spectrum of care, spanning primary care, secondary community care, tertiary and quaternary care services to post-acute through rehabilitation, palliative care and long-term care, while investing in world-class research and education.

Research is a cornerstone of Unity Health Toronto’s mission, bringing together world-class scientists, clinician-researchers, trainees, and research staff to advance discoveries that improve patient care and strengthen health systems. With internationally recognized strengths across clinical, scientific, and population health research, Unity Health is committed to translating innovative research into meaningful impact for patients, communities, and the broader healthcare system.

THE OPPORTUNITY

Clinical trials are a key part of Unity Health Toronto's Exceptional Care Without Exception strategic plan, advancing research excellence across the network while providing patients with access to innovative therapeutics that may not otherwise be available. SPHERE CRO , one of Canada's leading academically-affiliated Contract Research Organizations (CRO), complements this work by delivering end-to-end clinical research services to academic, pharmaceutical, biotechnology, and industry partners, including site management, project management, data management and technologies, regulatory affairs, biostatistics, and patient engagement.

A newly-created role reporting to the Chief Operating Officer, Research, and overseeing a team of approximately 50 people, the Senior Director will lead the execution of Unity’s clinical trials strategy, including the build of the Central Clinical Trials Unit, the adoption of key technologies such as the enterprise deployment of the clinical trials management system, and initiatives that position Unity’s sites as a global leader in clinical trials performance. The Senior Director will also lead the Industry Preferred Partnership Model, further fostering relationships with existing global pharmaceutical partners while pursuing new partnerships aligned with Unity’s clinical trials strategy. In addition, the role will oversee the financial and operational performance of SPHERE CRO, with full accountability for business development, client relationships, strategy, operations, and Profit and Loss (P&L) oversight.

Qualifications And Experience

10+ years of senior leadership experience in strategy and operations with a pharmaceutical portfolio including focus on research and development, biotechnology, or contract research organization (CRO).
MBA, Master of Science, or equivalent degree in a related field.
Demonstrated success building or transforming a clinical trials enterprise in partnership with global industry partners.
Experienced in successfully negotiating master agreements with global or large industry clients.
Demonstrated success operating a CRO or similar life sciences organization with regional or global studies to meet the needs of academic, industry and non-government organizational clients.
Demonstrated ability in leading business development or sales function of life sciences organizations, particularly related to a CRO.
Deep knowledge of ICH-GCP, Health Canada, FDA, EMA and applicable regulatory frameworks.
Experienced in managing large portfolio budgets including forecasting resourcing demands, pricing and profitability analysis, and variance analysis.
Superior interpersonal, influencing, and stakeholder relationship skills to foster alignment, goal congruence, and enthusiasm across clinical, institutional, and industry stakeholders.

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More about this job

Responsibilities

Lead Unity Health Toronto’s clinical trials strategy, including establishing the Central Clinical Trials Unit, deploying clinical trials technologies, improving site performance, and developing industry partnerships. Oversee SPHERE CRO’s business development, client relationships, strategy, operations, financial performance, and P&L, while leading a team of approximately 50 people.

Requirements

Requires 10 or more years of senior strategy and operations leadership in pharmaceuticals, research and development, biotechnology, or a CRO, along with an MBA, Master of Science, or equivalent related degree. Candidates should have experience building clinical trials enterprises, negotiating major industry agreements, operating a CRO, leading business development, applying relevant regulatory frameworks, and managing large budgets and stakeholder relationships.

Skills

Clinical Trials Strategy
Clinical Trials Operations
CRO Leadership
Business Development
Strategic Planning
Operational Performance Management
Profit And Loss Oversight
Master Agreement Negotiation
Clinical Research
Regulatory Affairs
ICH-GCP
Health Canada Regulations
FDA Regulations
EMA Regulations

Visa sponsorship

Not detected in the job text

Hiring contact

Chris Sawyer

Hiring contact email

chris.sawyer@lhhknightsbridge.com

Keywords

Clinical Trials
Contract Research Organization
CRO
Central Clinical Trials Unit
Clinical Trials Management System
Clinical Research
Site Management
Project Management
Data Management
Regulatory Affairs
Biostatistics
Patient Engagement
Business Development
Client Relationships
Industry Partnerships
Master Agreements
Profit And Loss
ICH-GCP
Health Canada
FDA
EMA
Budget Forecasting
Resource Planning
Pricing Analysis
Profitability Analysis
Variance Analysis
Pharmaceuticals
Biotechnology
Research And Development

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